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Faropenem is closely related, but it is a penem, not a carbapenem. [43] Antimicrobial resistance. NDM-1 is an enzyme that introduces bacterial resistance to carbapenem antibiotics via hydrolysis of the carbapenem backbone, thereby inactivating its ability to inhibit cell wall synthesis.
Meropenem, sold under the brand name Merrem among others, is an intravenous carbapenem antibiotic used to treat a variety of bacterial infections. [3] Some of these include meningitis, intra-abdominal infection, pneumonia, sepsis, and anthrax.
A carbapenam is a β-lactam compound that is a saturated carbapenem. [1] They exist primarily as biosynthetic intermediates on the way to the carbapenem antibiotics. Structure of (3S,5R)-carbapenam-3-carboxylic acid
In general, carbapenem, a β-lactam antibiotic, targets cells by inhibiting transpeptidases (penicillin-binding proteins). This prevents synthesis of peptidoglycan, a necessary structural component, leading to cell lysis. Resistance to carbapenem among Enterobacteriaceae and other gram-negative bacteria can be acquired through several mechanisms.
Bahasa Indonesia; Italiano; ... Pages in category "Carbapenem antibiotics" The following 18 pages are in this category, out of 18 total.
Biapenem is a carbapenem antibiotic. It has in vitro activity against anaerobes. It has in vitro activity against anaerobes. [ 1 ] 1-β-methyl-carbapenem antibiotic.
Imipenem alone is an effective antibiotic and can be given without cilastatin. Cilastatin itself does not have antibiotic activity, although it has been proved to be active against a zinc-dependent beta-lactamase that usually confers antibiotic resistance to certain bacteria, more precisely, the carbapenem family of antibiotics.
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