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  2. Human genetics - Wikipedia

    en.wikipedia.org/wiki/Human_genetics

    Medical genetics is the application of genetics to medical care. It overlaps human genetics, for example, research on the causes and inheritance of genetic disorders would be considered within both human genetics and medical genetics, while the diagnosis, management, and counseling of individuals with genetic disorders would be considered part ...

  3. List of genetic disorders - Wikipedia

    en.wikipedia.org/wiki/List_of_genetic_disorders

    The following is a list of genetic disorders and if known, type of mutation and for the chromosome involved. Although the parlance "disease-causing gene" is common, it is the occurrence of an abnormality in the parents that causes the impairment to develop within the child. There are over 6,000 known genetic disorders in humans.

  4. Genetic disorder - Wikipedia

    en.wikipedia.org/wiki/Genetic_disorder

    A genetic disorder is a health problem caused by one or more abnormalities in the genome. It can be caused by a mutation in a single gene (monogenic) or multiple genes (polygenic) or by a chromosome abnormality .

  5. Population bottleneck - Wikipedia

    en.wikipedia.org/wiki/Population_bottleneck

    Population bottleneck followed by recovery or extinction. A population bottleneck or genetic bottleneck is a sharp reduction in the size of a population due to environmental events such as famines, earthquakes, floods, fires, disease, and droughts; or human activities such as genocide, speciocide, widespread violence or intentional culling.

  6. Mendelian traits in humans - Wikipedia

    en.wikipedia.org/wiki/Mendelian_traits_in_humans

    Autosomal dominant A 50/50 chance of inheritance. Sickle-cell disease is inherited in the autosomal recessive pattern. When both parents have sickle-cell trait (carrier), a child has a 25% chance of sickle-cell disease (red icon), 25% do not carry any sickle-cell alleles (blue icon), and 50% have the heterozygous (carrier) condition. [1]

  7. Missing heritability problem - Wikipedia

    en.wikipedia.org/wiki/Missing_heritability_problem

    The missing heritability problem was named as such in 2008 (after the "missing baryon problem" in physics).The Human Genome Project led to optimistic forecasts that the large genetic contributions to many traits and diseases (which were identified by quantitative genetics and behavioral genetics in particular) would soon be mapped and pinned down to specific genes and their genetic variants by ...

  8. He Jiankui genome editing incident - Wikipedia

    en.wikipedia.org/wiki/He_Jiankui_genome_editing...

    The American Society of Human Genetics had declared in 2017 that the basic research on in vitro human genome editing on embryos and gametes should be promoted but that "At this time, given the nature and number of unanswered scientific, ethical, and policy questions, it is inappropriate to perform germline gene editing that culminates in human ...

  9. List of unsolved problems in biology - Wikipedia

    en.wikipedia.org/wiki/List_of_unsolved_problems...

    Unsolved problems relating to the structure and function of non-human organs, processes and biomolecules include: Korarchaeota (archaea). The metabolic processes of this phylum of archaea are so far unclear. Glycogen body. The function of this structure in the spinal cord of birds is not known. Arthropod head problem. A long-standing zoological ...