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  2. Pathophysiology of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of...

    Multiple sclerosis is an inflammatory demyelinating disease of the CNS in which activated immune cells invade the central nervous system and cause inflammation, neurodegeneration, and tissue damage. The underlying cause is currently unknown. Current research in neuropathology, neuroimmunology, neurobiology, and neuroimaging, together with ...

  3. Signs and symptoms of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of...

    The signs and symptoms of multiple sclerosis (MS) encompass a wide range of neurological and physical manifestations, including vision problems, muscle weakness, coordination difficulties, and cognitive impairment, varying significantly in severity and progression among individuals. Multiple sclerosis can cause a variety of symptoms: changes in ...

  4. Pathology of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Pathology_of_multiple...

    The retina nerve fiber layer (RNFL) is thinner than normal in MS patients. The procedure by which the MS underlying condition attacks the retina is currently unknown, but seems mediated by human leukocyte antigen-DR positive cells with the phenotype of microglia. MS patients show axonal loss in the retina and optic nerve, which can be measured ...

  5. Jean-Martin Charcot - Wikipedia

    en.wikipedia.org/wiki/Jean-Martin_Charcot

    t. e. Jean-Martin Charcot ( French: [ʃaʁko]; 29 November 1825 – 16 August 1893) was a French neurologist and professor of anatomical pathology. [2] He worked on groundbreaking work about hypnosis and hysteria, in particular with his hysteria patient Louise Augustine Gleizes. [3]

  6. Management of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Management_of_multiple...

    Management of multiple sclerosis. Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS). Several therapies for it exist, although there is no known cure. The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable ...

  7. Tumefactive multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Tumefactive_multiple_sclerosis

    Tumefactive multiple sclerosis is a condition in which the central nervous system of a person has multiple demyelinating lesions with atypical characteristics for those of standard multiple sclerosis (MS). It is called tumefactive as the lesions are "tumor-like" and they mimic tumors clinically, radiologically and sometimes pathologically.

  8. 32-year-old man becomes fully paralyzed within days of ...

    www.aol.com/news/32-old-man-becomes-fully...

    June 13, 2024 at 11:53 AM. In the fall of 2022, Dr. William Dugal, then 32, contracted Covid-19 and began experiencing unusual symptoms. “It started with the numbness in my feet, almost like my ...

  9. Progressive multifocal leukoencephalopathy - Wikipedia

    en.wikipedia.org/wiki/Progressive_multifocal_leu...

    Progressive multifocal leukoencephalopathy ( PML) is a rare and often fatal viral disease characterized by progressive damage ( -pathy) or inflammation of the white matter ( leuko-) of the brain ( -encephalo-) at multiple locations ( multifocal ). It is caused by the JC virus, which is normally present and kept under control by the immune system.