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Ligand-gated ion channels ( LICs, LGIC ), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open to allow ions such as Na +, K +, Ca 2+, and/or Cl − to pass through the membrane in response to the binding of a chemical messenger (i.e. a ligand ), such as a neurotransmitter.
Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore. Their functions include establishing a resting membrane potential, [1] shaping action potentials and other electrical signals by gating the flow of ions across the cell membrane, controlling the flow of ions across secretory and epithelial cells, and regulating cell volume. Ion channels are ...
Voltage-gated ion channels are a class of transmembrane proteins that form ion channels that are activated by changes in the electrical membrane potential near the channel. The membrane potential alters the conformation of the channel proteins, regulating their opening and closing. Cell membranes are generally impermeable to ions, thus they ...
Ion Television is a television network based in the United States made up of 44 owned-and-operated stations and 194 network affiliates, 164 of which broadcast as digital subchannels. [1] The Ion-owned stations are a part of the Ion Media unit of Scripps Networks, a wholly-owned subsidiary of the E. W. Scripps Company.
Transient receptor potential channel. Transient receptor potential channels ( TRP channels) are a group of ion channels located mostly on the plasma membrane of numerous animal cell types. Most of these are grouped into two broad groups: Group 1 includes TRPC ( "C" for canonical), TRPV ("V" for vanilloid ), TRPVL ("VL" for vanilloid-like), TRPM ...
A calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel, [1] which are a type of calcium channel regulated by changes in membrane potential. Some calcium channels are regulated by the binding of a ligand. [2] [3] Other calcium channels can also be ...
Voltage-gated calcium channels ( VGCCs ), also known as voltage-dependent calcium channels ( VDCCs ), are a group of voltage-gated ion channels found in the membrane of excitable cells ( e.g., muscle, glial cells, neurons, etc.) with a permeability to the calcium ion Ca 2+. [1] [2] These channels are slightly permeable to sodium ions, so they ...
Ion channels are typically categorised by gating mechanism and by the ion they conduct. Note that an ion channel may overlap between different categories. Some channels conduct multiple ion currents and some are gated by multiple mechanisms.