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DWI directly visualizes the ischemic necrosis in cerebral infarction in the form of a cytotoxic edema, [38] appearing as a high DWI signal within minutes of arterial occlusion. [39] With perfusion MRI detecting both the infarcted core and the salvageable penumbra, the latter can be quantified by DWI and perfusion MRI. [40]
Fluid-attenuated inversion recovery (FLAIR) is a magnetic resonance imaging sequence with an inversion recovery set to null fluids. For example, it can be used in brain imaging to suppress cerebrospinal fluid (CSF) effects on the image, so as to bring out the periventricular hyperintense lesions, such as multiple sclerosis (MS) plaques. [ 1 ]
Fluid-attenuated inversion recovery (FLAIR) [2] is an inversion-recovery pulse sequence used to nullify the signal from fluids. For example, it can be used in brain imaging to suppress cerebrospinal fluid so as to bring out periventricular hyperintense lesions, such as multiple sclerosis plaques.
Diffusion weighted (DWI) Conventional: DWI: Measure of Brownian motion of water molecules. [14] High signal within minutes of cerebral infarction (pictured). [15] Apparent diffusion coefficient: ADC: Reduced T2 weighting by taking multiple conventional DWI images with different DWI weighting, and the change corresponds to diffusion. [16]
The first MR images of a human brain were obtained in 1978 by two groups of researchers at EMI Laboratories led by Ian Robert Young and Hugh Clow. [1] In 1986, Charles L. Dumoulin and Howard R. Hart at General Electric developed MR angiography, [2] and Denis Le Bihan obtained the first images and later patented diffusion MRI. [3]
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to generate pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to form images of the organs in the body.
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Diffuse axonal injury after a motorcycle accident. MRI after 3 days: on T1-weighted images the injury is barely visible. On the FLAIR, DWI and T2*-weighted images a small bleed is identifiable. DAI is difficult to detect since it does not show up well on CT scans or with other macroscopic imaging techniques, though it shows up microscopically. [9]