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  2. Cannabis may be harmful to mental health. Experts explain why.

    www.aol.com/lifestyle/cannabis-may-harmful...

    There is also evidence that regular marijuana use can speed up the start of symptoms of mood disorders like bipolar disorder and major depression, along with anxiety disorders — especially in ...

  3. Animal models of depression - Wikipedia

    en.wikipedia.org/wiki/Animal_models_of_depression

    It is difficult to develop an animal model that perfectly reproduces the symptoms of depression in patients. It is generic that 3 standards may be used to evaluate the reliability of an animal version of depression: the phenomenological or morphological appearances (face validity), a comparable etiology (assemble validity), and healing similarities (predictive validity).

  4. Mood stabilizer - Wikipedia

    en.wikipedia.org/wiki/Mood_stabilizer

    Lithium – Lithium is the "classic" mood stabilizer, the first to be approved by the US FDA, and still popular in treatment. Therapeutic drug monitoring is required to ensure lithium levels remain in the therapeutic range: 0.6 to 0.8 or 0.8–1.2 mEq/L (or millimolar). Signs and symptoms of toxicity include nausea, vomiting, diarrhea, and ...

  5. Long-term effects of cannabis - Wikipedia

    en.wikipedia.org/wiki/Long-term_effects_of_cannabis

    A 2017 review suggests that cannabis has been shown to improve the mood of depression-diagnosed patients. [12] This is indicative of a longitudinal relationship between cannabis reduction and improvements in anxiety and depression. Anxiety and depression have been found to increase susceptibility to marijuana use. [52]

  6. Catatonic depression - Wikipedia

    en.wikipedia.org/wiki/Catatonic_depression

    Although symptoms of catatonic depression can vary by individual, common signs of catatonia include grimacing (making a facial expression of pain), negativism, posturing, rigidity, and waxy flexibility. [1] Major depressive symptoms are also experienced by a person suffering from catatonic depression. [1]

  7. Psilocybin - Wikipedia

    en.wikipedia.org/wiki/Psilocybin

    Clinical trials, including both open-label trials and double-blind randomized controlled trials, have found that single doses of psilocybin produce rapid and long-lasting antidepressant effects outperforming placebo in people with major depressive disorder and treatment-resistant depression. [205]

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