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The bifurcated needle was created as a more efficient and cost effective alternative to the jet injector previously in use. It was invented in 1965 by Dr. Benjamin Rubin , working at Wyeth Laboratories, and was the primary instrument used during the World Health Organization 's 1966–1977 campaign to eradicate smallpox . [ 5 ]
This is the earliest documented jet injector to administer water or medicine under enough pressure to penetrate the skin without the use of a needle. [20] 1920s: Diesel engines began to be made in large quantities: thus the start of serious risk of accidental jet-injection by their fuel injectors in workshop accidents.
A booster dose is an extra administration of a vaccine after an earlier dose. After initial immunization , a booster provides a re-exposure to the immunizing antigen . It is intended to increase immunity against that antigen back to protective levels after memory against that antigen has declined through time.
accelerate the syringe forward, puncturing the injection site; actuate the piston of the syringe, injecting the drug; deploy a shield to cover the needle; Some injectors are triggered by simply pushing the nose ring against the injection site. In these designs, the protective cap is the primary safety.
Injector pens may also remove stigma or fear around the use of injection medication in public environments, such as insulin before a meal at a restaurant. [2] Combination injector pens which include multiple medications used to treat a disease are designed to reduce the number of injections a person must use to administer their medications. [3]
Intraosseous infusion (IO) is the process of injecting medication, fluids, or blood products directly into the bone marrow; [1] this provides a non-collapsible entry point into the systemic venous system. [2]
An intramuscular injection of vaccines allows for a slow release of the antigen to stimulate the body's immune system and to allow time for developing antibodies. Subcutaneous injections are used by heroin addicts (called 'skin popping', referring to the bump formed by the bolus of heroin), to sustain a slow release that staves off withdrawal ...
In pharmacokinetics, a loading dose is an initial higher dose of a drug that may be given at the beginning of a course of treatment before dropping down to a lower maintenance dose. [ 1 ] A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life .
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