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The Compendium of Pharmaceuticals and Specialties: The Canadian Drug Reference for Health Professionals, more commonly known by its abbreviation CPS, [1] is a reference book that contains drug monographs and numerous features which help healthcare professionals prescribe and use drugs safely and appropriately.
Carbonate derivatives of 14β-hydroxycodeine "viz., 14β-hydroxy-6-O-(methoxycarbonyl)codeine, 6-O-methoxycarbonyl-14β-(methoxycarbonyloxy)codeine, and 14β-acetoxy-6-O-methoxy-carbonylcodeine, potential substrates for ring C modification in morphinane (sic) alkaloids, were synthesized for the first time."
The Canadian model is based on the American drug court system, which aimed to reduce prison overcrowding after it was found that up to three-quarters of the prison population growth could be attributed to drug offenders. One example of a Canadian drug court is found in Toronto, where one has been operating since 1998. Of the 284 drug offenders ...
Prescription drug addiction is the chronic, repeated use of a prescription drug in ways other than prescribed for, including using someone else’s prescription. [ 3 ] [ 4 ] A prescription drug is a pharmaceutical drug that may not be dispensed without a legal medical prescription .
Opioid-related deaths in Ontario had increased by 242% from 1969 to 2014. [135] By 2009 in Ontario there were more deaths from oxycodone overdoses than from cocaine overdoses. [136] Deaths from opioid pain relievers had increased from 13.7 deaths per million residents in 1991 to 27.2 deaths per million residents in 2004. [137]
As such, historically each province has managed their own pharmaceutical system, from formularies to public prescription drug programs, in different ways. [3] This meant that health technology assessments were performed independently by a patchwork of organizations, with some provinces, like Quebec and British Columbia having their own in-house ...
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From 2011 to 2021, prescription opioid deaths per year remained stable, while synthetic opioid deaths per year increased from 2,600 overdoses to 70,601. [24] Since 2018, fentanyl and its analogues have been responsible for most drug overdose deaths in the United States, causing over 71,238 deaths in 2021.