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α-Tocopherol (alpha-tocopherol) is a type of vitamin E.Its E number is "E307". Vitamin E exists in eight different forms, four tocopherols and four tocotrienols.All feature a chromane ring, with a hydroxyl group that can donate a hydrogen atom to reduce free radicals and a hydrophobic side chain, along with an aromatic ring is situated near the carbonyls in the fatty acyl chains of the ...
Tocopherols (/ t oʊ ˈ k ɒ f ə ˌ r ɒ l /; [1] TCP) are a class of organic compounds comprising various methylated phenols, many of which have vitamin E activity. Because the vitamin activity was first identified in 1936 from a dietary fertility factor in rats, it was named tocopherol, from Greek τόκος tókos 'birth' and φέρειν phérein 'to bear or carry', that is 'to carry a ...
General chemical structure of tocopherols RRR alpha-tocopherol; chiral points are where the three dashed lines connect to the side chain. The nutritional content of vitamin E is defined by equivalency to 100% RRR-configuration α-tocopherol activity.
Related: Cancer-Causing 'Forever Chemicals' Found in Many Kinds of Contact Lenses, Study Finds The issue, the statement says, comes from a synthetic polymer called fluoroelastomer, which is used ...
At room temperature, α-tocopheryl acetate is a fat-soluble liquid. It has 3 chiral centers and thus 8 stereoisomers. It is made by esterifying α-tocopherol with acetic acid. 2R,4R,8R-isomer, also known as RRR-α-tocopheryl acetate, is the most common isomer used for various purposes. This is because α-tocopherol occurs in nature primarily as ...
The mechanism of action of arsenic trioxide is complex and not fully understood. Generally, the drug inhibits the proliferation of cancer cells and induces their differentiation and/or apoptosis, which can occur in various ways depending on the involved organelles and biochemical processes. Arsenic trioxide induces apoptosis through:
Targeted alpha-particle therapy (or TAT) is an in-development method of targeted radionuclide therapy of various cancers. It employs radioactive substances which undergo alpha decay to treat diseased tissue at close proximity. [1] It has the potential to provide highly targeted treatment, especially to microscopic tumour cells.
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