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Mucocutaneous leishmaniasis is an especially disturbing form of cutaneous leishmaniasis, because it produces destructive and disfiguring lesions of the face. It is most often caused by Leishmania braziliensis, but cases caused by L. aethiopica have also been described. [10] Mucocutaneous leishmaniasis is very difficult to treat.
Leishmaniasis is a wide array of clinical manifestations caused by protozoal parasites of the Trypanosomatida genus Leishmania. [7] It is generally spread through the bite of phlebotomine sandflies, Phlebotomus and Lutzomyia, and occurs most frequently in the tropics and sub-tropics of Africa, Asia, the Americas, and southern Europe.
Allopurinol is used to reduce urate formation in conditions where urate deposition has already occurred or is predictable. The specific diseases and conditions where it is used include gouty arthritis, skin tophi, kidney stones, idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate ...
Allopurinol hypersensitivity syndrome (AHS) typically occurs in persons with preexisting kidney failure. [3]: 119 Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption [3]: 119 or, less commonly, develops one of the far more serious and potentially lethal severe cutaneous adverse reactions viz., the DRESS syndrome, Stevens Johnson syndrome, or toxic epidermal ...
Miltefosine, sold under the trade name Impavido among others, is a medication mainly used to treat leishmaniasis and free-living amoeba infections such as Naegleria fowleri and Balamuthia mandrillaris. [4] This includes the three forms of leishmaniasis: cutaneous, visceral and mucosal. [5] It may be used with liposomal amphotericin B or ...
Leishmania / l iː ʃ ˈ m eɪ n i ə,-ˈ m æ n-/ [1] is a parasitic protozoan, a single-celled organism of the genus Leishmania that is responsible for the disease leishmaniasis. [2] [3] [4] They are spread by sandflies of the genus Phlebotomus in the Old World, and of the genus Lutzomyia in the New World.
Leishmania infantum is the causative agent of infantile visceral leishmaniasis in the Mediterranean region [1] and in Latin America, where it has been called Leishmania chagasi. [ 2 ] [ 3 ] It is also an unusual cause of cutaneous leishmaniasis , [ 4 ] which is normally caused by specific lineages (or zymodemes).
[citation needed] However, when the host is infected, the Leishmania can cause 3 different forms of Leishmaniasis. For this species, it has been known to cause cutaneous leishmaniasis and mucocutaneous leishmaniasis. Cutaneous leishmaniasis is commonly characterized with skin lesions, which can appear localized, or throughout the body.