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Nodular regenerative hyperplasia (NRH) is a rare liver disease, characterised by the growth of nodules within the liver, resulting in liver hyperplasia.While in many cases it is asymptomatic and thus goes undetected – or is only discovered incidentally while investigating some other medical condition – in some people it results in non-cirrhotic portal hypertension (NCPH).
Focal nodular hyperplasia (FNH) is the second most common benign tumor of the liver. [2] FNH is found in 0.2%– 0.3% of adults worldwide. [2] FNH is more common in females (10:1 female to male ratio) except in Japan and China, in which there is a more equal prevalence of cases between females and males. [2]
Benign liver tumors generally develop on normal or fatty liver, are single or multiple (generally paucilocular), have distinct delineation, with increased echogenity (hemangiomas, benign focal nodular hyperplasia) or absent, with posterior acoustic enhancement effect (cysts), have distinct delineation (hydatid cyst), lack of vascularization or show a characteristic circulatory pattern ...
Focal nodular hyperplasia's most recognizable gross feature is a central stellate scar seen in 60–70% of cases. Microscopically, a lobular proliferation of bland-appearing hepatocytes with a bile ductular proliferation and malformed vessels within the fibrous scar is the most common pattern.
Nodular regenerative hyperplasia, a liver condition; North Richland Hills, Texas, U.S. MedStar National Rehabilitation Hospital, Washington, DC, U.S. Nutritional Rehabilitation Homes of the Nepal Youth Foundation; nrh (trigraph), romanization for Hmong /ɳɖʱ/ Norman Regional Hospital, or Norman Regional Health, a medical system in Norman ...
Papillae vs pseudopapillae: True papillae are outgrowths of epithelium, surrounding fibrovascular cores of stroma and at least one blood vessel. In contrast, pseudopapillae (such as in solid pseudopapillary tumours) are nests of proliferating cells that eventually grow to become almost back-to-back, with cells in the centers of nests disintegrating, leaving rims of cells lining the periphery ...
- Foveolar hyperplasia (black arrow), as a tortuosity in the "neck" region of the gastric glands. - Scant or minimal inflammatory cells (white arrow), i.e. lack of large numbers of neutrophils and plasma cells.. - Smooth muscle hyperplasia in the lamina propria (in black oval). The diagnosis is by examination of tissue, e.g. a stomach biopsy.
Oral fibroma, traumatic fibroma, focal intraoral fibrous hyperplasia, fibrous nodule, oral polyp: Irritation fibroma on the left cheek of a 40-year-old man. Histopathology of irritation fibroma. Low magnification (left) characteristically [1] shows a nonencapsulated nodular mass. High magnification (right) shows fibrous connective tissue with ...