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Macrolides belong to the polyketide class of natural products. Some macrolides have antibiotic or antifungal activity and are used as pharmaceutical drugs. Rapamycin is also a macrolide and was originally developed as an antifungal, but has since been used as an immunosuppressant drug and is being investigated as a potential longevity ...
Carrimycin is a macrolide antibiotic.It was approved by the National Medical Products Administration of China in 2019. [1] It is approved for the treatment of acute tracheal bronchitis caused by Haemophilus influenzae, Streptococcus pneumoniae, and for the treatment of acute sinusitis caused by S. pneumoniae, H. influenzae, Streptococcus pyogenes, Moraxella catarrhalis, and Staphylococcus. [2]
Josamycin is a macrolide antibiotic. It was isolated by Hamao Umezawa and his colleagues from strains of Streptomyces narbonensis var. josamyceticus var. nova in 1964. [1] [2] It is currently sold in various countries.Brand examples are: Europe: Josalid, Josacine, Iosalide, Josamina; Russia: Wilprafen (Вильпрафен) Japan: Josamy
Nitrofurantoin has historically been reported to be a disulfiram-like drug and to produce alcohol intolerance-type reactions when combined with alcohol. [53] However, subsequent clinical studies failed to replicate these findings and the earlier results have been deemed erroneous.
Some drugs can inhibit CYP3A4, which means they reduce its activity and increase the blood levels of the drugs that depend on it for elimination. This can lead to adverse effects or drug-drug interactions. [47] Azithromycin is a member of macrolides that are a class of antibiotics with a cyclic structure with a lactone ring and sugar moieties ...
Ketolide antibiotics (4 P) Pages in category "Macrolide antibiotics" The following 45 pages are in this category, out of 45 total.
The fosfomycin molecule has an epoxide or oxirane ring, which is highly strained and thus very reactive. [citation needed]Fosfomycin has broad antibacterial activity against both Gram-positive and Gram-negative pathogens, with useful activity against E. faecalis, E. coli, and various Gram-negatives such as Citrobacter and Proteus.
Roxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. but with an N-oxime side chain attached to the ring. Roxithromycin was patented in 1980 and approved for medical use in 1987. [1]