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Proctosedyl is the brand name for a family of two products with identical active ingredients designed to treat a variety of proctological disorders. One is a topical ointment, the other a rectal suppository. In the United Kingdom both products are contract manufactured by Patheon Limited on behalf of the Sanofi-Aventis group.
Cinchocaine is the active ingredient in some topical hemorrhoid creams such as Proctosedyl. [3] It is also a component of the veterinary drug Somulose, used for euthanasia of horses and cattle . Physical properties
Several different ingredients can be used to form the base of a suppository: cocoa butter or a similar substitute, polyethylene glycol, hydrogels, and glycerinated gelatin. The type of material used depends on the type of suppository, the type of drug, and the conditions in which the suppository will be stored.
The active ingredient in Anusol ointment and suppositories is zinc sulfate monohydrate which helps decrease the irritation in the area and acts as an astringent.The active ingredient in Anusol plus is zinc sulfate monohydrate and pramoxine HCL, which is antipruritic (also found in Gold Bond). [1]
Antioxidants are used to prevent gel ingredients from being oxidised. [3] When choosing the antioxidant to be used, it is important to consider the nature of the solvent. [ 3 ] Since the solvent of most gels are aqueous in nature, water-soluble antioxidants are more commonly used. [ 3 ]
Vicks VapoRub is a mentholated topical ointment, part of the Vicks brand of over-the-counter medications owned by the American consumer goods company Procter & Gamble. VapoRub is intended for use on the chest , back and throat for cough suppression or on muscles and joints for minor aches and pains.
The topical cream formulation has a higher content of oily substance than gel, but a lower content of oily ingredient than ointment. Therefore, the viscosity of topical cream formulation lies between gel and ointment. [1] The pharmacological effect of the topical cream formulation is confined to the skin surface or within the skin. [3]
Germolene's active ingredients include phenol 1.2% (providing antiseptic, locally analgesic and antipruritic effects) and chlorhexidine digluconate 0.25%. The Germoloids line of Germolene products, intended for use on haemorrhoids , also includes zinc oxide , and the analgesic lidocaine hydrochloride .