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Similar to the NINCDS-ADRDA Alzheimer's Criteria are the DSM-IV-TR criteria published by the American Psychiatric Association. [3] At the same time the advances in functional neuroimaging techniques such as PET or SPECT that have already proven their utility to differentiate Alzheimer's disease from other possible causes, [4] have led to proposals of revision of the NINCDS-ADRDA criteria that ...
The clinical diagnostic criteria were revised in the late 1990s, when the FTD spectrum was divided into a behavioral variant, a nonfluent aphasia variant, and a semantic dementia variant. [20] The most recent revision of the clinical research criteria was by the International Behavioural Variant FTD Criteria Consortium in 2011. [50]
11 C-PiB is currently the most studied and used radioligand for PET imaging of cerebral Aβ pathology. [2] This technique has been implicated in Alzheimer's disease research whereby scientists involved in this field are able to perform noninvasive in vivo neuroimaging studies using PET scans in brains of individuals with various degrees of dementia.
Positron emission tomography (PET) [1] is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption.
Due to low accuracy, the C-PIB-PET scan is not recommended as an early diagnostic tool or for predicting the development of AD when people show signs of mild cognitive impairment (MCI). [160] The use of 18 F-FDG PET scans, as a single test, to identify people who may develop Alzheimer's disease is not supported by evidence. [161]
Pre-dementia or early-stage dementia (stages 1, 2, and 3). In this initial phase, a person can still live independently and may not exhibit obvious memory loss or have any difficulty completing ...
294.1x Dementia due to Huntington's disease (coded 294.1 in the DSM-IV) 294.1x Dementia due to Pick's disease (coded 290.10 in the DSM-IV) 294.1x Dementia due to Creutzfeldt–Jakob disease (coded 290.10 in the DSM-IV) 294.1x Dementia due to ... [Indicate the general medical condition not listed above] (coded 294.1 in the DSM-IV) 294.8 Dementia NOS
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