Search results
Results from the WOW.Com Content Network
Smooth muscle relaxation (Experimental histamine H 2 receptor agonist used for asthma and COPD) Inhibit antibody synthesis, T-cell proliferation and cytokine production; Vasodilation – PKA activity causes phosphorylation of MLCK, decreasing its activity, resulting in MLC of myosin being dephosphorylated by MLCP and thus inhibiting contraction ...
H1 receptors are linked to allergic responses, H2 to gastric acid regulation, H3 to neurotransmitter release modulation, and H4 to immune system function. There are four known histamine receptors: H 1 receptor H1 Receptors: These receptors are primarily located on smooth muscle cells, endothelial cells, and neurons.
A histamine agonist is a drug which causes increased activity at one or more of the four histamine receptor subtypes. H 1 agonists promote wakefulness. [1] H 2: Betazole and Impromidine are examples of agonists used in diagnostics to increase histamine. H 3: Betahistine is a weak Histamine 1 agonist and a very strong antagonist of the Histamine ...
Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.
A muscle synergy is composed of agonist and synergistic muscles. An agonist muscle is a muscle that contracts individually, and it can cause a cascade of motion in neighboring muscles. Synergistic muscles aid the agonist muscles in motor control tasks, but they act against excess motion that the agonists may create.
Unlike traditional walking, Nordic walking engages your upper body by incorporating the arms and shoulders into the exercise, which research suggests can help improve cardiovascular fitness and ...
“The proportion of slow-twitch to fast-twitch muscle fibers in a particular muscle varies depending on the function of the muscle and the type of training in which an individual participates.
GLP-1 receptor agonists: These work by mimicking the effects of the naturally occurring hormone GLP-1, which regulates appetite and food intake. By activating GLP-1 receptors in your brain, GLP-1s ...