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PUVA (psoralen and UVA) is an ultraviolet light therapy treatment for skin diseases: vitiligo, eczema, psoriasis, graft-versus-host disease, mycosis fungoides, large plaque parapsoriasis, and cutaneous T-cell lymphoma, using the sensitizing effects of the drug psoralen.
[1] [2] "Proper use" is generally defined as reaching the "Sub-Erythemic Dose" (S.E.D.), the maximum amount of UVB your skin can receive without burning. Certain fungal growths under the toenail can be treated using a specific wavelength of UV delivered from a high-power LED (light-emitting diode) and can be safer than traditional systemic drugs.
[2] Artificial UV light sources from tanning units and phototherapy treatment units can also trigger PLE. About three-quarters of patients acquire PLE after UV-A exposure only, one-tenth after UV-B exposure only, and the rest after a combination of UV-A and UV-B exposure. [6] People vary in the amount of sun exposure needed to trigger the rash ...
Psoralen plus UVA (PUVA) therapy can be used to treat hyperproliferative skin disorders like psoriasis and certain kinds of skin cancer. [2] Unfortunately, PUVA treatment itself leads to a higher risk of skin cancer. [3] An important use of psoralen is in PUVA treatment for skin problems such as psoriasis and, to a lesser extent, eczema and ...
A period of four to six weeks should involve 3–4 radiation sessions. The most frequently applied form of light therapy is PUVA therapy. This first treats the hands with a cream that contains an ingredient that causes the skin to become light-sensitive, the hands are then irradiated with ultraviolet A light (UV-A). After two days of treatment ...
Eczema, the itchy inflammatory skin condition, has been on the rise since the 1970s. New research finds that pollution may be causing eczema "hot spots." High rates of eczema could be caused by ...
Another option is natural and artificial UV radiation since it can inhibit the growth of Malassezia yeast. [31] Some recommend photodynamic therapy using UV-A and UV-B laser or red and blue LED light to inhibit the growth of Malassezia fungus and reduce seborrhoeic inflammation. [31] [32] [33]
It is a specialized form of light therapy. First formulated in 1925 by American dermatologist William H. Goeckerman (1884–1954), Goeckerman therapy continues to be used due to its efficacy and safety profile. [1] Individual institutions have modified the Goeckerman regimen and developed their own protocols.
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