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Paclitaxel total synthesis in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol). [1] This diterpenoid is an important drug in the treatment of cancer but, also expensive because the compound is harvested from a scarce resource, namely the Pacific yew ( Taxus brevifolia ).
Paclitaxel, sold under the brand name Taxol among others, is a chemotherapy medication used to treat ovarian cancer, esophageal cancer, breast cancer, lung cancer, Kaposi's sarcoma, cervical cancer, and pancreatic cancer. [11] It is administered by intravenous injection. [11] There is also an albumin-bound formulation. [11]
Using electrophoresis, they were able to isolate the two major components, taxine A and taxine B. taxine A was the fastest moving band and accounted for 1.3% of the alkaloid mixture, while taxine B was the slowest moving band and accounted for 30% of the mixture. [17] The full structure of taxine A was reported in 1982, [1] taxine B in 1991. [18]
Intel's co-CEOs discussed splitting the firm's manufacturing and products businesses Thursday. A separation could address Intel's poor financial performance.
Taxus wallichiana is also a source of the chemical precursors to the anticancer drug paclitaxel (taxol). [7] Taxus wallichiana is used for making tea by the Bhotiya tribal community in the Garhwal Himalaya. The stem bark of this species, which is locally known as thuner, is collected for this purpose.
Cult folk musician and painter Ed Askew has died. He was 84 years old. PEOPLE can confirm that Askew had been battling "ongoing health struggles" and he had been in hospice care.
2013 June 1 [67] Original mod was called CnC Reborn. Tower Unite: Garry's Mod: 2009 July 7 2016 April 8 Tower Unite is the standalone version of GMod Tower by Pixeltail Games, which was a mod for Garry's Mod. Garry's Mod, in turn, was a mod for Half-Life 2. Tremulous: Quake III Arena: 2005 August 11 2006 March 31
Economists are keeping a close eye on inflation and labor reports amid speculation as to timing of future cuts to the Fed rate, with inflation data indicating a continued decline from a peak of 9. ...