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Duloxetine is a serotonin and norepinephrine reuptake inhibitor (SNRI). It is taken orally, most commonly as an antidepressant, often in an extended-release tablet form.
Duloxetine, sold under the brand name Cymbalta among others, [1] is a medication used to treat major depressive disorder, generalized anxiety disorder, obsessive-compulsive disorder, fibromyalgia, neuropathic pain and central sensitization. [10] [11] It is taken by mouth. [10] Duloxetine is a serotonin–norepinephrine reuptake inhibitor (SNRI ...
[6] [78] In 1998 a survey conducted in England found that 85% of the general practitioners that had prescribed the antidepressant nefazodone were unaware of SS. [43] The incidence may be increasing as a larger number of pro-serotonergic drugs (drugs which increase serotonin levels) are now being used in clinical practice. [69]
Dual inhibition of serotonin and noradrenaline reuptake can offer advantages over other antidepressant drugs by treating a wider range of symptoms. [3] They can be especially useful in concomitant chronic or neuropathic pain. [4] SNRIs, along with SSRIs and NRIs, are second-generation antidepressants.
List of SNRIs. Numerous SNRI antidepressants are currently prescribed to treat depression, as well as other mood disorders.They include: Desvenlafaxine (Pristiq) has been used as a treatment for ...
Switching directly is usually only a safe option for switching between certain SSRIs and SNRIs with short half-lives, as these medications are less likely to cause drug interactions or unwanted ...
Vyvanse (lisdexamfetamine) – a pro-drug stimulant used to treat attention deficit hyperactivity disorder and binge eating disorder; Vyvanse is converted into Dexedrine in vivo; Viibryd – an antidepressant of the serotonin modulator and stimulators class; Vivactil (protriptyline) an antidepressant also used in the treatment of nerve pain
Researchers have found that escitalopram, paroxetine, and duloxetine are the antidepressants tied to the highest risk of weight gain. ... (SSRIs), serotonin/norepinephrine reuptake inhibitors ...