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A problem statement is a description of an issue to be addressed, or a condition to be improved upon. It identifies the gap between the current problem and goal. The first condition of solving a problem is understanding the problem, which can be done by way of a problem statement. [1]
In applying statistics to a scientific, industrial, or social problem, it is conventional to begin with a statistical population or a statistical model to be studied. Populations can be diverse groups of people or objects such as "all people living in a country" or "every atom composing a crystal".
Though there are many approximate solutions (such as Welch's t-test), the problem continues to attract attention [4] as one of the classic problems in statistics. Multiple comparisons: There are various ways to adjust p-values to compensate for the simultaneous or sequential testing of hypotheses. Of particular interest is how to simultaneously ...
Real-world evidence (RWE) in medicine is the clinical evidence regarding the usage and potential benefits or risks of a medical product derived from analysis of real-world data (RWD). RWE can be generated by different study designs or analyses, including but not limited to, randomized trials, including large simple trials, pragmatic trials, and ...
In statistics, imputation is the process of replacing missing data with substituted values. When substituting for a data point, it is known as "unit imputation"; when substituting for a component of a data point, it is known as "item imputation".
The use of real-world data from electronic health records and digital health-monitoring devices is also given as an example of general Post-Market Clinical Followup (PMCF) information for medical devices in the guideline "MDCG 2022-21 Guidance on Periodic Safety Update Report (PSUR) according to Regulation (EU) 2017/745 (MDR)" from December 2022.
In science and engineering, root cause analysis (RCA) is a method of problem solving used for identifying the root causes of faults or problems. [1] It is widely used in IT operations, manufacturing, telecommunications, industrial process control, accident analysis (e.g., in aviation, [2] rail transport, or nuclear plants), medical diagnosis, the healthcare industry (e.g., for epidemiology ...
A research question is "a question that a research project sets out to answer". [1] Choosing a research question is an essential element of both quantitative and qualitative research. Investigation will require data collection and analysis, and the methodology for this will vary widely.