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Dermatomyositis is an autoimmune disorder featuring both humoral and T-cell autoimmune processes. [3] Dermatomyositis may develop as a paraneoplastic syndrome associated with several forms of malignancy. [4] It is known to be associated with several viruses, especially coxsackievirus, but no definitive causal link has been found. [3]
Gottron's sign is a pathognomonic cutaneous manifestation associated with dermatomyositis (DM), which is an inflammatory disorder affecting the skin and muscles. [1] The primary lesion of dermatomyositis appears as a violaceous, macular erythema with a symmetric distribution, which may progress and become poikilodermatous (atrophic with telangiectasia and pigmentary changes) and indurated (as ...
It can also be associated with underlying cancer. The main classes of idiopathic inflammatory myopathy are polymyositis (PM), dermatomyositis (DM) (including juvenile, amyopathic, and sine-dermatitis form), inclusion-body myositis (IBM), immune-mediated necrotising myopathy (IMNM), and focal autoimmune myositis. [1]
The three main types of idiopathic myositis (known as inflammatory myopathies) that typically test positive for autoantibodies are dermatomyositis, polymyositis, and inclusion body myositis. [4] Other autoimmune diseases, such as systemic lupus erythematosus , can also cause myositis-like symptoms.
Juvenile dermatomyositis (JDM) is an idiopathic inflammatory myopathy (IMM) of presumed autoimmune dysfunction resulting in muscle weakness among other complications. It manifests itself in children; it is the pediatric counterpart of dermatomyositis .
Image credits: VastCoconut2609 Cognitively, pessimistic headlines and stories reinforce our negativity bias, which, according to Ruiz-McPherson, "can lead to maladaptive thought patterns ...
Dermatomyositis: Skin and muscles: Anti-Jo1, Anti-Mi2, Anti-SRP, Anti-TIF1 Confirmed 9 in 1,000,000 [10] Discoid lupus erythematosus: Skin ANA, Anti-dsDNA, Anti-Sm Confirmed Part of SLE prevalence (20-150 per 100,000) [11] Epidermolysis bullosa acquisita: Skin Anti-type VII collagen Confirmed Extremely rare [12] Erythema nodosum: Skin None ...
Amy Schumer once hopped on board the Ozempic trend, but the side effects were so intense she had to stop.. During a recent appearance on "The Howard Stern Show," the comedian, 43, opened up about ...