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  2. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    Metformin inhibits cyclic AMP production, blocking the action of glucagon, and thereby reducing fasting glucose levels. [117] Metformin also induces a profound shift in the faecal microbial community profile in diabetic mice, and this may contribute to its mode of action possibly through an effect on glucagon-like peptide-1 secretion. [108]

  3. 7 Benefits of Metformin (Including Weight Loss) - AOL

    www.aol.com/7-benefits-metformin-including...

    Metformin (and the brand-name versions, Riomet and Glucophage) isn’t used by people with type 1 diabetes, an autoimmune disorder wherein the body does not make insulin. Metformin can have side ...

  4. List of largest selling pharmaceutical products - Wikipedia

    en.wikipedia.org/wiki/List_of_largest_selling...

    Rank Brand Name(s) Generic Name Sales Q1 2014 Sales ($000) Change from Q4 2013 Company(ies) Disease/Medical Use First Approval Date Patent Expiration Date [6] [7]; 1: Abilify

  5. Diabetes medication - Wikipedia

    en.wikipedia.org/wiki/Diabetes_medication

    Typical reduction in glycated hemoglobin (A1C) values for Metformin is 1.5–2.0% Metformin (Glucophage) may be the best choice for patients who also have heart failure, [10] but it should be temporarily discontinued before any radiographic procedure involving intravenous iodinated contrast, as patients are at an increased risk of lactic acidosis.

  6. Common diabetes drug may help slow organ aging, monkey study ...

    www.aol.com/lifestyle/common-diabetes-drug-may...

    The type 2 diabetes drug metformin helped slow aging across multiple organs, including the brain, kidneys, and the skin, a study in cynomolgus monkeys has shows. Common diabetes drug may help slow ...

  7. Is There a "Best Time" to Take Metformin? - AOL

    www.aol.com/best-time-metformin-115700262.html

    Some people take metformin once, twice, or even three times a day, depending on the type of metformin (tablet or liquid) and how many milligrams they’re prescribed. Again, aim to take it at the ...

  8. Pharmaceutical industry in Pakistan - Wikipedia

    en.wikipedia.org/wiki/Pharmaceutical_industry_in...

    The pharmaceutical industry in Pakistan was estimated to be worth Rs. 748 billion (US$2.6 billion) in 2023, representing about 1% of the country's GDP. [ 1 ] The industry is largely import-dependent, with more than 90% of raw material being imported and only 12% of active pharmaceutical ingredients locally produced. [ 1 ]

  9. Sitagliptin - Wikipedia

    en.wikipedia.org/wiki/Sitagliptin

    Sitagliptin, sold under the brand name Januvia among others, is an anti-diabetic medication used to treat type 2 diabetes. [8] In the United Kingdom it is listed as less preferred than metformin or a sulfonylurea. [9] It is taken by mouth. [8] It is also available in the fixed-dose combination medication sitagliptin/metformin (Janumet, Janumet ...

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