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The cell cycle is a series of complex, ordered, sequential events that control how a single cell divides into two cells, and involves several different phases. The phases include the G1 and G2 phases, DNA replication or S phase, and the actual process of cell division, mitosis or M phase. [1]
This is an accepted version of this page This is the latest accepted revision, reviewed on 19 February 2025. Process in which chromosomes are replicated and separated into two new identical nuclei For the type of cell division in sexually reproducing organisms used to produce gametes, see Meiosis. For excessive constriction of the pupils, see Miosis. For the parasitic infestation, see Myiasis ...
The G 1 phase, gap 1 phase, or growth 1 phase, is the first of four phases of the cell cycle that takes place in eukaryotic cell division. In this part of interphase , the cell synthesizes mRNA and proteins in preparation for subsequent steps leading to mitosis.
The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.
It can also happen during mitotic division, [1] which may result in loss of heterozygosity. Crossing over is important for the normal segregation of chromosomes during meiosis. [ 2 ] Crossing over also accounts for genetic variation, because due to the swapping of genetic material during crossing over, the chromatids held together by the ...
Three types of cell division: binary fission (taking place in prokaryotes), mitosis and meiosis (taking place in eukaryotes).. When cells are ready to divide, because cell size is big enough or because they receive the appropriate stimulus, [20] they activate the mechanism to enter into the cell cycle, and they duplicate most organelles during S (synthesis) phase, including their centrosome.
Germ cells, or gametes, undergo meiosis, while somatic cells will undergo mitosis. After the cell proceeds successfully through the M phase, it may then undergo cell division through cytokinesis. The control of each checkpoint is controlled by cyclin and cyclin-dependent kinases. The progression of interphase is the result of the increased ...
The G2 to M transition is dramatic; there is an all-or-nothing effect, and the transition is irreversible. This is advantageous to the cell because entering mitosis is a critical step in the life cycle of a cell. If it does not fully commit, the cell would run into many issues with partially dividing, ultimately likely leading to the cell's death.