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  2. Intracardiac injection - Wikipedia

    en.wikipedia.org/wiki/Intracardiac_injection

    The practice of intracardiac injection originated in the 1800s. It was commonly performed during the 1960s, as it was considered the fastest way to get medication to the heart. The practice began declining during the 1970s as more reliable delivery methods (i.e., intravenous, endotracheal, and intraosseous) came into use. Around that time ...

  3. Dobutamine - Wikipedia

    en.wikipedia.org/wiki/Dobutamine

    Dobutamine is a medication used in the treatment of cardiogenic shock (as a result of inadequate tissue perfusion) and severe heart failure. [2] [3] It may also be used in certain types of cardiac stress tests. [2] It is given by IV only, as an injection into a vein or intraosseous as a continuous infusion. [2]

  4. Cardiac marker - Wikipedia

    en.wikipedia.org/wiki/Cardiac_marker

    Cardiac markers are biomarkers measured to evaluate heart function. They can be useful in the early prediction or diagnosis of disease. [1] Although they are often discussed in the context of myocardial infarction, other conditions can lead to an elevation in cardiac marker level. [2] [3]

  5. γ-L-Glutamyl-L-cysteine - Wikipedia

    en.wikipedia.org/wiki/Γ-L-Glutamyl-L-cysteine

    γ-L-Glutamyl-L-cysteine, also known as γ-glutamylcysteine (GGC), is a dipeptide found in animals, plants, fungi, some bacteria, and archaea.It has a relatively unusual γ-bond between the constituent amino acids, L-glutamic acid and L-cysteine and is a key intermediate in the γ-glutamyl cycle first described by Meister in the 1970s.

  6. Pericardial effusion - Wikipedia

    en.wikipedia.org/wiki/Pericardial_effusion

    If the effusion is compromising heart function and causing cardiac tamponade, it will need to be drained. [1] Fluid can be drained via needle pericardiocentesis as discussed above or surgical procedures, such as a pericardial window. [2] The intervention used depends on the cause of pericardial effusion and the clinical status of the patient.

  7. Transfusion-associated circulatory overload - Wikipedia

    en.wikipedia.org/wiki/Transfusion-associated...

    The symptoms of TACO can include shortness of breath , low blood oxygen levels , leg swelling (peripheral edema), high blood pressure (hypertension), and a high heart rate (tachycardia). [ 3 ] It can occur due to a rapid transfusion of a large volume of blood but can also occur during a single red blood cell transfusion (about 15% of cases). [ 2 ]

  8. Wiggers diagram - Wikipedia

    en.wikipedia.org/wiki/Wiggers_diagram

    A Wiggers diagram modified from [1]. A Wiggers diagram, named after its developer, Carl Wiggers, is a unique diagram that has been used in teaching cardiac physiology for more than a century.

  9. Pathophysiology of heart failure - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of_heart...

    The main pathophysiology of heart failure is a reduction in the efficiency of the heart muscle, through damage or overloading. As such, it can be caused by a wide number of conditions, including myocardial infarction (in which the heart muscle is starved of oxygen and dies), hypertension (which increases the force of contraction needed to pump blood) and cardiac amyloidosis (in which misfolded ...

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