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The WHO has called the emergence of drug-resistant pathogens one of the top 10 global public health threats facing humanity and has identified gonorrhea in particular as a priority pathogen.
N. gonorrhoeae has a high affinity for horizontal gene transfer, and as a result, the existence of any strain resistant to a given drug could spread easily across strains. [citation needed] Cases of Neisseria Gonorrhoeae with decreased susceptibility or resistance to antibiotics (2017-2018).
Zoliflodacin (development codes AZD0914 and ETX0914) is an experimental antibiotic that is being studied for the treatment of infection with Neisseria gonorrhoeae (). [1] It has a novel mechanism of action which involves inhibition of bacterial type II topoisomerases. [2]
Each drug should be administered as a single dose, with the gentamicin entering intramuscularly at a concentration of 240 mg, along with 2 g of azithromycin taken orally. [75] If an individual is not allergic to cephalosporins but ceftriaxone is unavailable, an alternative treatment is a single dose of 800 mg cefixime consumed orally. [ 75 ]
“If you don’t have gonorrhea, you can’t get drug-resistant gonorrhea,” says Hamill, “so use tried and trusted ways such as condoms to prevent acquiring gonorrhea in the first place ...
A study out of the University of York shows that carbon monoxide-releasing molecules could be the key to developing a new antibiotic to treat gonorrhea.
Norfloxacin, sold under the brand name Noroxin among others, is an antibiotic [1] [2] that belongs to the class of fluoroquinolone antibiotics.It is used to treat urinary tract infections, gynecological infections, inflammation of the prostate gland, gonorrhea and bladder infection.
Ceftriaxone, sold under the brand name Rocephin, is a third-generation cephalosporin antibiotic used for the treatment of a number of bacterial infections. [4] These include middle ear infections, endocarditis, meningitis, pneumonia, bone and joint infections, intra-abdominal infections, skin infections, urinary tract infections, gonorrhea, and pelvic inflammatory disease. [4]
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