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45.4 million / 0.6% (2015, global) [5] Deaths. 107,000 (2015, global) [6] Syphilis (/ ˈsɪfəlɪs /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary. [1][2] The primary stage classically ...
The history of syphilis has been well studied, but the exact origin of the disease remains unknown. [3] It appears to have originated in both Africa and America. [4] [5] As such, there are two primary hypotheses: one proposes that syphilis was carried to Europe from the Americas by the crew(s) of Christopher Columbus as a byproduct of the Columbian exchange, while the other proposes that ...
Congenital syphilis. Notched incisors known as Hutchinson's teeth which are characteristic of congenital syphilis. Specialty. Infectious diseases. Symptoms. Rash, fever, large liver and spleen, skeletal abnormalities [1] Usual onset. Unborn baby, newborn baby or later [1] Duration.
The Tuskegee Study of Untreated Syphilis in the Negro Male[1] (informally referred to as the Tuskegee Experiment or Tuskegee Syphilis Study) was a study conducted between 1932 and 1972 by the United States Public Health Service (PHS) and the Centers for Disease Control and Prevention (CDC) on a group of nearly 400 African American men with ...
In 2021, there were 77.9 cases of congenital syphilis per 100,000 live births. Disease intervention specialists often link infected mothers and their partners with care for syphilis, which has ...
Neurosyphilis is the infection of the central nervous system in a patient with syphilis. In the era of modern antibiotics, the majority of neurosyphilis cases have been reported in HIV-infected patients. [citation needed] Meningitis is the most common neurological presentation in early syphilis. Tertiary syphilis symptoms are exclusively ...
Chancre. A chancre (/ ˈʃæŋkər / SHANG-kər) [1] is a painless genital ulcer most commonly formed during the primary stage of syphilis. [2] This infectious lesion forms around 21 days after the initial exposure to Treponema pallidum, the gram-negative spirochaete bacterium causing syphilis, but can range from 10 to 90 days. [2]
Infectious disease. Bejel, or endemic syphilis, is a chronic skin and tissue disease caused by infection by the endemicum subspecies of the spirochete Treponema pallidum. Bejel is one of the "endemic treponematoses" (endemic infections caused by spiral-shaped bacteria called treponemes), a group that also includes yaws and pinta.
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