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Infobox references. Dehydroepiandrosterone (DHEA), also known as androstenolone, is an endogenous steroid hormone precursor. [4] It is one of the most abundant circulating steroids in humans. [5] DHEA is produced in the adrenal glands, [6] the gonads, and the brain. [7]
Dehydroepiandrosterone sulfate, abbreviated as DHEA sulfate or DHEA-S, also known as androstenolone sulfate, is an endogenous androstane steroid that is produced by the adrenal cortex. [1] It is the 3β- sulfate ester and a metabolite of dehydroepiandrosterone (DHEA) and circulates in far greater relative concentrations than DHEA. [ 2 ]
DHEA supplements were shown to help women with adrenal insufficiency, improving depression, anxiety, mood and overall well-being. Research in men and women with Addison’s disease showed that 50 ...
1:1000 to 1:50 (nonclassical forms) Congenital adrenal hyperplasia due to 21-hydroxylase deficiency (CAH) is a genetic disorder characterized by impaired production of cortisol in the adrenal glands. [1] It is classified as an inherited metabolic disorder. CAH is an autosomal recessive condition since it results from inheriting two copies of ...
Variants in genes responsible the enzymes required for the synthesis of cortisol in the adrenal cortex. Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders characterized by impaired cortisol synthesis. [1][2] It results from the deficiency of one of the five enzymes required for the synthesis of cortisol in the ...
Prasterone, also known as dehydroepiandrosterone (DHEA) and sold under the brand name Intrarosa among others, is a medication as well as over-the-counter dietary supplement which is used to correct DHEA deficiency due to adrenal insufficiency or old age, as a component of menopausal hormone therapy, to treat painful sexual intercourse due to vaginal atrophy, and to prepare the cervix for ...
7-Keto-DHEA. Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). 7-Ketodehydroepiandrosterone (7-keto-DHEA, 7-oxo-DHEA), also known as 7-oxoprasterone, is a steroid prohormone produced by metabolism of the prohormone dehydroepiandrosterone (DHEA). [1][2]
[1] [2] It is the 3α-epimer of dehydroepiandrosterone (DHEA; androst-5-en-3β-ol-17-one) and the 5(6)-dehydrogenated and non-5α-reduced analogue of androsterone (5α-androstan-3α-ol-17-one). [2] DHA is produced in and secreted from the adrenal glands , along with other weak androgens like DHEA, androstenediol , and androstenedione .
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