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Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant and eugeroic (wakefulness promoter) medication used primarily to treat narcolepsy, [3] [8] [15] a sleep disorder characterized by excessive daytime sleepiness and sudden sleep attacks. [16]
[3] [2] [4] The modafinil analogues are of interest in the potential treatment of a condition involving the misuse of stimulant drugs (psychostimulant use disorder or PSUD), as drugs that help increase motivation (pro-motivational agents) to treat motivational disorders, [4] [5] [6] and for treatment of neurodegenerative diseases such as ...
[3] [4] Eugeroics are also often prescribed off-label for the treatment of EDS in idiopathic hypersomnia. [11] In contrast to classical psychostimulants , such as amphetamine and methylphenidate , which are also used in the treatment of these disorders, eugeroics typically do not produce euphoria , and, consequently, have lower misuse potential .
FIU, Nicklaus Children’s test cancer against 120 drugs. As part of the trial, which involved more than a dozen pediatric cancer patients, Logan had samples of his blood sent to an FIU lab.
Which one patients get can depend on where they get treatment. After three years, 57% of those who got chemo and surgery were alive, compared to 51% of those who got chemo, surgery and radiation.
Meta-analytic evidence showed that add-on modafinil and armodafinil were more effective than placebo on response to treatment, clinical remission, and reduction in depressive symptoms, with only minor side effects, but the effect sizes are small and the quality of evidence has to be considered low, limiting the clinical relevance of current ...
Patients were followed for two years in a preliminary analysis; Hwang plans to continue following the women and comparing their cancer rates at five years and 10 years.
The systems of the body most affected by chemotherapy drugs include visual and semantic memory, attention and motor coordination and executive functioning. [9] [10] These effects can impair a chemotherapy patient's ability to understand and make decisions regarding treatment, perform in school or employment and can reduce quality of life. [10]
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