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A plaque caused by asbestos exposure on the diaphragmatic pleura: Specialty: Pulmonology: Symptoms: Shortness of breath, cough, wheezing, chest pain [1] Complications: Lung cancer, mesothelioma, pleural fibrosis, pulmonary heart disease [1] [2] Usual onset ~10-40 years after long-term exposure [3] Causes: Asbestos [4] Diagnostic method
Asbestos-related diseases are disorders of the lung and pleura caused by the inhalation of asbestos fibres. Asbestos-related diseases include non-malignant disorders such as asbestosis (pulmonary fibrosis due to asbestos), diffuse pleural thickening, pleural plaques, pleural effusion, rounded atelectasis and malignancies such as lung cancer and malignant mesothelioma.
Asbestos exposure can also cause pleural effusion, diffuse pleural fibrosis, pleural plaques, and non-mesothelioma lung cancer. Smoking greatly increases the lung cancer risk of asbestos exposure. [3] Residents and workers of asbestos mining centers such as the town of Asbest, Russia experience dangerous exposure to asbestos and asbestos dust. [9]
Pleural plaques are patchy collections of hyalinized collagen in the parietal pleura. [2] They have a holly leaf appearance on X-ray. [1] They are indicators of asbestos exposure, and the most common asbestos-induced lesion. [3] They usually appear after 20 years or more of exposure and never degenerate into mesothelioma.
Pleural contamination with asbestos or other mineral fibers has been shown to cause cancer. Long thin asbestos fibers (blue asbestos, amphibole fibers) are more potent carcinogens than "feathery fibers" (chrysotile or white asbestos fibers). [28] However, there is now evidence that smaller particles may be more dangerous than the larger fibers.
Asbestos warning label. Figure A shows the location of the lungs, airways, pleura, and diaphragm in the body. Figure B shows lungs with asbestos-related diseases, including pleural plaque, lung cancer, asbestosis, plaque on the diaphragm, and mesothelioma. Left-sided mesothelioma (seen on the right of the picture): chest CT
This is a shortened version of the eighth chapter of the ICD-9: Diseases of the Respiratory System. It covers ICD codes 460 to 519. The full chapter can be found on pages 283 to 300 of Volume 1, which contains all (sub)categories of the ICD-9. Volume 2 is an alphabetical index of Volume 1.
Pleural mesothelioma, almost always caused by exposure to asbestos dust. In addition, since many cancers spread via the bloodstream and the entire cardiac output passes through the lungs, it is common for cancer metastases to occur within the lung. Breast cancer may invade directly through local spread, and through lymph node metastases.