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Intravenous iron infusions can cause skin rash, hives, itchiness and flush. Skin staining and discolouration can occur at the site of infusion if the iron and saline solution leaks outside the vein into the surrounding tissue. [ 14 ]
The researchers found iron infusions reduced the risk of hospitalisation due to heart failure and dying from a heart related cause by 18% compared to usual care.
In serious cases, iron chelation may be needed by intravenous injection, like deferoxamine. It binds iron and other metal ions with the chelator and is eliminated through the urine. Supportive care may also be necessary for patients with breathing difficulty and GI upset, by offering mechanical ventilation and rehydration respectively . [10]
Iron infusions are for people who don’t tolerate supplements well, have a tough time absorbing iron, or for people who need to boost their levels quickly. “Intravenous iron is very efficient ...
The iron sucrose molecule is a polymer with two main molecules; sucrose (chemical formula C 12 H 22 O 11) and an iron (III) hydroxide (Na 2 Fe 5 O 8 •3(H 2 O)). These two components are in solution together, but are not bound to one another. [2] Iron sucrose is a type II complex, with two oxygen atoms bonded to each iron atom. [3]
Overall, hemoglobin was 0.71g/dl higher than those treated with oral iron supplements. Iron stores in the liver, estimated by serum ferritin, were also 224.84 μg/L higher in those receiving IV-iron. [58] However, there was also low-certainty evidence that allergic reactions were more likely following IV-iron therapy.
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