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Difference between Z-test and t-test: Z-test is used when sample size is large (n>50), or the population variance is known. t-test is used when sample size is small (n<50) and population variance is unknown. There is no universal constant at which the sample size is generally considered large enough to justify use of the plug-in test.
The table shown on the right can be used in a two-sample t-test to estimate the sample sizes of an experimental group and a control group that are of equal size, that is, the total number of individuals in the trial is twice that of the number given, and the desired significance level is 0.05. [4]
The Z-factor defines a characteristic parameter of the capability of hit identification for each given assay. The following categorization of HTS assay quality by the value of the Z-Factor is a modification of Table 1 shown in Zhang et al. (1999); [2] note that the Z-factor cannot exceed one.
Suppose we are using a Z-test to analyze the data, where the variances of the pre-treatment and post-treatment data σ 1 2 and σ 2 2 are known (the situation with a t-test is similar). The unpaired Z-test statistic is ¯ ¯ / + /, The power of the unpaired, one-sided test carried out at level α = 0.05 can be calculated as follows:
Simple back-of-the-envelope test takes the sample maximum and minimum and computes their z-score, or more properly t-statistic (number of sample standard deviations that a sample is above or below the sample mean), and compares it to the 68–95–99.7 rule: if one has a 3σ event (properly, a 3s event) and substantially fewer than 300 samples, or a 4s event and substantially fewer than 15,000 ...
Comparison of the various grading methods in a normal distribution, including: standard deviations, cumulative percentages, percentile equivalents, z-scores, T-scores. In statistics, the standard score is the number of standard deviations by which the value of a raw score (i.e., an observed value or data point) is above or below the mean value of what is being observed or measured.
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This ensures that the hypothesis test maintains its specified false positive rate (provided that statistical assumptions are met). [35] The p-value is the probability that a test statistic which is at least as extreme as the one obtained would occur under the null hypothesis. At a significance level of 0.05, a fair coin would be expected to ...