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  2. Voltage clamp - Wikipedia

    en.wikipedia.org/wiki/Voltage_clamp

    From the point of view of control theory, the voltage clamp experiment can be described in terms of the application of a high-gain output feedback control law [13] to the neuronal membrane. [14] Mathematically, the membrane voltage can be modeled by a conductance-based model with an input given by the applied current I a p p ( t ...

  3. Perceptual control theory - Wikipedia

    en.wikipedia.org/wiki/Perceptual_control_theory

    Perceptual control theory (PCT) is a model of behavior based on the properties of negative feedback control loops. A control loop maintains a sensed variable at or near a reference value by means of the effects of its outputs upon that variable, as mediated by physical properties of the environment.

  4. Attenuator (genetics) - Wikipedia

    en.wikipedia.org/wiki/Attenuator_(genetics)

    Attenuation is a second mechanism of negative feedback in the trp operon. While the TrpR repressor decreases transcription by a factor of 70, attenuation can further decrease it by a factor of 10, thus allowing accumulated repression of about 700-fold. Attenuation is made possible by the fact that in prokaryotes (which have no nucleus), the ...

  5. Event-related potential - Wikipedia

    en.wikipedia.org/wiki/Event-related_potential

    The ERP is plotted with negative voltages upward, a common, but not universal, practice in ERP research. An event-related potential (ERP) is the measured brain response that is the direct result of a specific sensory, cognitive, or motor event. [1] More formally, it is any stereotyped electrophysiological response to a stimulus.

  6. Bistability - Wikipedia

    en.wikipedia.org/wiki/Bistability

    This signaling network illustrates the simultaneous positive and negative feedback loops whose exquisite sensitivity helps create a bistable switch. Bistability can only arise in biological and chemical systems if three necessary conditions are fulfilled: positive feedback , a mechanism to filter out small stimuli and a mechanism to prevent ...

  7. Depolarization - Wikipedia

    en.wikipedia.org/wiki/Depolarization

    In the process of depolarization, the negative internal charge of the cell temporarily becomes more positive (less negative). This shift from a negative to a more positive membrane potential occurs during several processes, including an action potential. During an action potential, the depolarization is so large that the potential difference ...

  8. Stress (biology) - Wikipedia

    en.wikipedia.org/wiki/Stress_(biology)

    In biology, most biochemical processes strive to maintain equilibrium (homeostasis), a steady state that exists more as an ideal and less as an achievable condition. Environmental factors, internal or external stimuli, continually disrupt homeostasis; an organism's present condition is a state of constant flux moving about a homeostatic point ...

  9. Long-term depression - Wikipedia

    en.wikipedia.org/wiki/Long-term_depression

    There is a positive feedback loop that results from a simultaneous input of signals from PF-CF and increases DAG and Ca 2+ in Purkinje dendritic spines. Calcium and DAG activate conventional PKC (cPKC), which then activates MAPKKK and the rest of the MAPK cascade. Activated MAPK and Ca 2+ activate PLA2, AA and cPKC creating a positive feedback ...