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2. Branched-chain amino acid - Wikipedia

   en.wikipedia.org/wiki/Branched-chain_amino_acid

   The BCKDH complex converts branched-chain amino acids into acyl-CoA derivatives, which after subsequent reactions are converted either into acetyl-CoA or succinyl-CoA that enter the citric acid cycle. [7] Enzymes involved are branched chain aminotransferase and 3-methyl-2-oxobutanoate dehydrogenase.

3. Branched-chain alpha-keto acid dehydrogenase complex

   en.wikipedia.org/wiki/Branched-chain_alpha-keto...

   A deficiency in any of the enzymes of this complex as well as an inhibition of the complex as a whole leads to a buildup of branched-chain amino acids and their harmful derivatives in the body. These accumulations lend a sweet smell to bodily excretions (such as ear wax and urine), leading to a pathology known as maple syrup urine disease .

4. Branched-chain amino acid aminotransferase - Wikipedia

   en.wikipedia.org/wiki/Branched-chain_amino_acid...

   The BCAT enzyme catalyzes the conversion of BCAAs and α-ketoglutarate into branched chain α-keto acids and glutamate. The structure to the right of branched chain amino acid aminotransferase was found using X-ray diffraction with a resolution of 2.20 Å. The branched-chain amino acid aminotransferase found in this image was isolated from ...

5. BCKDK - Wikipedia

   en.wikipedia.org/wiki/BCKDK

   BCKDK regulates the activity of branched-chain α-ketoacid dehydrogenase complex (BCKD) through phosphorylation and inactivation. This inactivation results in increased branched-chain amino acids (BCAA), which is seen to reduce oxidative stress; however, having too much BCAA has been proven to be toxic to humans. Therefore, BCKDK is a vital ...

6. BCKDHA - Wikipedia

   en.wikipedia.org/wiki/BCKDHA

   The second major step in the catabolism of the branched-chain amino acids (isoleucine, leucine, and valine) is catalyzed by the branched-chain alpha-keto acid dehydrogenase complex (BCKD; EC 1.2.4.4), an inner-mitochondrial enzyme complex that consists of 3 catalytic components: a heterotetrameric (alpha2, beta2) branched-chain alpha-keto acid decarboxylase (E1), a homo-24-meric dihydrolipoyl ...

7. Cahill cycle - Wikipedia

   en.wikipedia.org/wiki/Cahill_cycle

   The Cahill cycle, also known as the alanine cycle or glucose-alanine cycle, [1] is the series of reactions in which amino groups and carbons from muscle are transported to the liver. [2] It is quite similar to the Cori cycle in the cycling of nutrients between skeletal muscle and the liver. [1]