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Feline immunodeficiency virus (FIV) is a Lentivirus that affects cats worldwide, with 2.5% to 4.4% [1] [2] of felines being infected.. FIV was first isolated in 1986, by Niels C Pedersen and Janet K. Yamamoto at the UC Davis School of Veterinary Medicine in a colony of cats that had a high prevalence of opportunistic infections and degenerative conditions and was originally called Feline T ...
Feline leukemia virus (FeLV) is a retrovirus that infects cats.FeLV can be transmitted from infected cats when the transfer of saliva or nasal secretions is involved. If not defeated by the animal's immune system, the virus weakens the cat's immune system, which can lead to diseases which can be lethal.
Feline vaccination is animal vaccination applied to cats. Vaccination plays a vital role in protecting cats from infectious diseases , some of which are potentially fatal. They can be exposed to these diseases from their environment, other pets, or even humans.
In a large group of cats, n, the epidemiological risk of mutation (E) is higher and expressed theoretically as: E = n 2 −n. A house hosting 2 cats therefore has risk of mutation E = 2. When 4 kittens (6 cats in total) are born into this house, the risk increases from 2 to 30 (6 2 −6). Overcrowding increases the risk of mutation and ...
The human vaccine development process generally takes 10 to 15 years, whereas the animal vaccine process only takes an average 5 to 7 years to produce. [23] Albeit, the ability to prioritise potential vaccine targets and the use of studies to test safety is less in the animal vaccine production compared to human vaccines. [24]
In addition, individual genetic characteristics can also contribute to these injection-site sarcomas. [9] The incidence of VAS is between 1 in 1,000 to 1 in 10,000 vaccinated cats and has been found to be dose-dependent. [1] The time from vaccination to tumor formation varies from three months to eleven years. [10]
It is the main plasma metabolite of the antiviral prodrug remdesivir, and has a half-life of around 24 hours in human patients. Remdesivir and GS-441524 were both found to be effective in vitro against feline coronavirus strains responsible for feline infectious peritonitis (FIP), a lethal systemic disease affecting domestic cats.
Transmission of the infection to the human from the cat has been attributed to kissing the cat, providing care that exposes the person to the body fluids of the cat and sleeping with the cat. [ 1 ] [ 10 ] [ 3 ] Kittens are more likely to transmit the bacterium than adult cats. [ 10 ]