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Melatonin is the most popular over-the-counter sleep remedy in the United States, resulting in sales in excess of US$400 million during 2017. [70] In 2022, it was the 217th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [26] [27]
Melatonin supplements for sleep come with side effects and their use may raise safety concerns, experts say. There's little evidence they help with insomnia.
While melatonin is generally considered safe, it can have side effects or interfere with medication. Here's how and when to use this sleep-promoting supplement, according to experts.View Entire ...
Melatonin is used both as a prescription medication and an over-the-counter dietary supplement for the management of sleep disorders, including insomnia and various circadian rhythm sleep disorders such as delayed sleep phase disorder, jet lag disorder, and shift work sleep disorder. [55]
The most common side effects include headache, dizziness and nausea, Dr. Raj Dasgupta, a physician specializing in sleep medicine, internal medicine, pulmonary care and critical care, tells Yahoo ...
A 2009 pooled analysis of four clinical trials found that ramelteon at a dose of 8 mg reduced sleep onset by 13 minutes (30% decrease) relative to placebo on the first and second nights of use. [11] Subsequent meta-analyses of longer-duration use have found that ramelteon decreases subjective sleep latency by about 4 to 7 minutes.
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