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Hydralazine is a medication used to treat high blood pressure. Approximately 5% of the patients who have taken hydralazine over long periods of time and in high doses have shown DIL-like symptoms. [8] Many of the other drugs have a low to very low risk to develop DIL. The following table shows the risk of development of DIL of some of these ...
Chlorthalidone is the thiazide drug that is most strongly supported by the evidence as providing a mortality benefit; in the ALLHAT study, a chlorthalidone dose of 12.5 mg was used, with titration up to 25 mg for those subjects who did not achieve blood pressure control at 12.5 mg. Chlorthalidone has repeatedly been found to have a stronger ...
Antihypertensive agents comprise multiple classes of compounds that are intended to manage hypertension (high blood pressure). Antihypertensive therapy aims to maintain a blood pressure goal of <140/90 mmHg in all patients, as well as to prevent the progression or recurrence of cardiovascular diseases (CVD) in hypertensive patients with established CVD. [2]
The effect of treatment of blood pressure between 130/80 mmHg and 160/100 mmHg is less clear, with some reviews finding benefit [6] [16] [17] [18] and others finding unclear benefit. [19] [20] High blood pressure affects 33% of the population globally. [9] About half of all people with high blood pressure do not know that they have it. [9]
Cyclophosphamide increases the risk of developing infections, pancreas problems, high blood sugar, and high blood pressure. [119] Hydroxychloroquine was approved by the FDA for lupus in 1955. [120] Some drugs approved for other diseases are used for SLE 'off-label'.
There are also a few types of medications, including certain antibiotics as well as seizure, anti-inflammatory and blood pressure treatments, that can trigger drug-induced lupus erythematosus, or ...
This includes high blood pressure in pregnancy and very high blood pressure resulting in symptoms. [3] It has been found to be particularly useful in heart failure, together with isosorbide dinitrate, for treatment of people of African descent. [2] It is given by mouth or by injection into a vein. [3]
The most commonly reported side effects are diarrhea, high blood pressure, nausea, respiratory infection, dizziness, increased liver enzymes, rash, abdominal pain, fatigue, chest pain and decreased white blood cell count. [4] [3] The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. [5]