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Reye's syndrome is a potentially fatal disease that causes numerous detrimental effects to many organs, especially the brain and liver, as well as causing hypoglycemia. [20] The exact cause is unknown, and while it has been associated with aspirin consumption by children with viral illness, it also occurs in the absence of aspirin use.
IP1867B is a potential brain cancer treatment under development by Innovate Pharmaceuticals for use in the treatment of brain tumors, by combining reformulated aspirin with two additional ingredients, into a soluble form. [1] Developing a true liquid aspirin has long been a scientific goal.
Specific inflammatory conditions that aspirin is used to treat include Kawasaki disease, pericarditis, and rheumatic fever. [10] Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk. [10] For pain or fever, effects typically begin within 30 minutes. [10]
Overall, the risk of developing colorectal cancer over a 10-year period was 1.98% among participants who used aspirin regularly, compared with 2.95% for people who didn’t use aspirin regularly.
Resistance is a major cause of treatment failure in chemotherapeutic drugs. There are a few possible causes of resistance in cancer, one of which is the presence of small pumps on the surface of cancer cells that actively move chemotherapy from inside the cell to the outside.
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Microtubules are essential to mitotic reproduction, so through the inactivation of the microtubule function of a cell, taxanes inhibit cell division. Paclitaxel—used to treat lung cancer, ovarian cancer, breast cancer, and advanced forms of Kaposi's sarcoma. [21] Docetaxel—used to treat breast, ovarian, and non-small cell lung cancer. [22] [23]
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