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A glycogen storage disease(GSD, also glycogenosisand dextrinosis) is a metabolic disordercaused by a deficiency of an enzymeor transport proteinaffecting glycogen synthesis, glycogen breakdown, or glucose breakdown, typically in musclesand/or livercells. [1] GSD has two classes of cause: genetic and environmental.
Glycogen storage disease type I (GSD I) is an inherited disease that prevents the liver from properly breaking down stored glycogen, which is necessary to maintain adequate blood sugar levels. GSD I is divided into two main types, GSD Ia and GSD Ib, which differ in cause, presentation, and treatment. There are also possibly rarer subtypes, the ...
Gestational diabetes is a condition in which a woman without diabetes develops high blood sugar levels during pregnancy. [ 2 ] Gestational diabetes generally results in few symptoms; [ 2 ] however, it increases the risk of pre-eclampsia, depression, and of needing a Caesarean section. [ 2 ] Babies born to individuals with poorly treated ...
For example, if there is a gestational age based on the beginning of the last menstrual period of 9.0 weeks, and a first-trimester obstetric ultrasonography gives an estimated gestational age of 10.0 weeks (with a 2 SD variability of ±8% of the estimate, thereby giving a variability of ±0.8 weeks), the difference of 1.0 weeks between the ...
The female body goes through a variety of physical changes during pregnancy, including alterations to the brain. ... this process happens early in development, again during puberty, and pregnancy ...
Glycogen storage disease type V (GSD5, GSD-V), [ 1 ] also known as McArdle's disease, [ 2 ] is a metabolic disorder, one of the metabolic myopathies, more specifically a muscle glycogen storage disease, caused by a deficiency of myophosphorylase. [ 3 ][ 4 ] Its incidence is reported as one in 100,000, roughly the same as glycogen storage ...
In terms of the diagnosis for glycogen storage disease type III, the following tests/exams are carried out to determine if the individual has the condition: [9] [10] Biopsy (muscle or liver) CBC; Ultrasound; DNA mutation analysis (helps ascertain GSD III subtype)
Diabetes pregnancy management. [] Blood glucose levels in pregnant women should be regulated as strictly as possible. During the first weeks of pregnancy less insulin treatment is required due to tight blood sugar control as well as the extra glucose needed for the growing fetus. [ 11 ] At this time basal and bolus insulin may need to be ...