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Shaw has done controversial research on the alleged adverse effects of vaccines, including publishing two 2011 reports about the effect of aluminum adjuvants in vaccines. [3] [4] The World Health Organization's Global Advisory Committee on Vaccine Safety criticized the two 2011 reports, calling them "seriously flawed". [5]
These hypotheses have been investigated, with the conclusion that currently used vaccines meet high safety standards and that criticism of vaccine safety in the popular press is not justified. [ 56 ] [ 101 ] [ 132 ] [ 133 ] Large well-controlled epidemiologic studies have been conducted and the results do not support the hypothesis that ...
In immunology, an adjuvant is a substance that increases or modulates the immune response to a vaccine. [ 1 ] The word "adjuvant" comes from the Latin word adiuvare, meaning to help or aid. "An immunologic adjuvant is defined as any substance that acts to accelerate, prolong, or enhance antigen-specific immune responses when used in combination ...
The Vaccine Adverse Event Reporting System (VAERS) is a United States program for vaccine safety, co-managed by the U.S. Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA). [1] VAERS is a postmarketing surveillance program, collecting information about adverse events (possible harmful side effects) that ...
Human challenge study. A human challenge study, also called a challenge trial or controlled human infection model (CHIM), is a type of clinical trial for a vaccine or other pharmaceutical involving the intentional exposure of the test subject to the condition tested. [1][2][3] Human challenge studies may be ethically controversial because they ...
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Vaccine is a peer-reviewed medical journal, published by Elsevier. It is targeted towards medical professionals who are interested in vaccinology, vaccines, and vaccination. The official journal of the Edward Jenner Society and the Japanese Society for Vaccinology, Vaccine describes itself as "an interface between academics, those in research ...
AS04. Adjuvant System 04 or AS04 is a trade name for a combination of adjuvants used in various vaccine products by GlaxoSmithKline, [ 1 ] in particular the Fendrix [ 2 ] hepatitis B vaccine and Cervarix [ 3 ] human papillomavirus (HPV) vaccine. It consists of aluminium hydroxide and monophosphoryl lipid A (MPL).