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  2. Donepezil - Wikipedia

    en.wikipedia.org/wiki/Donepezil

    Donepezil, sold under the brand name Aricept among others, is a medication used to treat dementia of the Alzheimer's type. [3][4][8] It appears to result in a small benefit in mental function and ability to function. [9] Use, however, has not been shown to change the progression of the disease. [10]

  3. Dementia with Lewy bodies - Wikipedia

    en.wikipedia.org/wiki/Dementia_with_Lewy_bodies

    Medical condition Dementia with Lewy bodies Other names Diffuse Lewy body disease, dementia due to Lewy body disease Microscopic image of a Lewy body (arrowhead) in a neuron of the substantia nigra ; scale bar=20 microns (0.02 mm) Specialty Neurology, psychiatry Symptoms Dementia, abnormal behavior during REM sleep, fluctuations in alertness, visual hallucinations, parkinsonism Usual onset ...

  4. Memantine - Wikipedia

    en.wikipedia.org/wiki/Memantine

    Memantine when added to donepezil in those with moderate-to-severe dementia resulted in "limited improvements" in a 2017 review. [24] The UK National Institute for Clinical Excellence (NICE) issued guidance in 2018 recommending consideration of the combination of memantine with donepezil in those with moderate-to-severe dementia.

  5. Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Alzheimer's_disease

    Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens, [2] and is the cause of 60–70% of cases of dementia. [2][15] The most common early symptom is difficulty in remembering recent events. [1] As the disease advances, symptoms can include problems with language, disorientation (including ...

  6. Hachiro Sugimoto - Wikipedia

    en.wikipedia.org/wiki/Hachiro_Sugimoto

    Sugimoto was born as the eighth child among nine children in a downtown section of Tokyo in 1943, and joined Eisai, a Japanese pharmaceutical company. [3] While working for Eisai, he graduated from Chuo University in 1969 and obtained his doctorate in pharmacology at Hiroshima University in 2002. [3] In 2003, he retired from Eisai, and became ...

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