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  2. Preload (cardiology) - Wikipedia

    en.wikipedia.org/wiki/Preload_(cardiology)

    Preload is related to the ventricular end-diastolic volume; a higher end-diastolic volume implies a higher preload. However, the relationship is not simple because of the restriction of the term preload to single myocytes. Preload can still be approximated by the inexpensive echocardiographic measurement end-diastolic volume or EDV.

  3. Pressure–volume loop analysis in cardiology - Wikipedia

    en.wikipedia.org/wiki/Pressure–volume_loop...

    Afterload is the mean tension produced by a chamber of the heart in order to contract. It can also be considered as the ‘load’ that the heart must eject blood against. Afterload is, therefore, a consequence of aortic large vessel compliance, wave reflection, and small vessel resistance (LV afterload) or similar pulmonary artery parameters (RV afterload

  4. Afterload - Wikipedia

    en.wikipedia.org/wiki/Afterload

    Afterload is the pressure that the heart must work against to eject blood during systole (ventricular contraction). Afterload is proportional to the average arterial pressure. [ 1 ] As aortic and pulmonary pressures increase, the afterload increases on the left and right ventricles respectively.

  5. Frank–Starling law - Wikipedia

    en.wikipedia.org/wiki/Frank–Starling_law

    The three curves illustrate that shifts along the same line indicate a change in preload, while shifts from one line to another indicate a change in afterload or contractility. A blood volume increase would cause a shift along the line to the right, which increases left ventricular end diastolic volume (x axis), and therefore also increases ...

  6. Heart failure - Wikipedia

    en.wikipedia.org/wiki/Heart_failure

    The degree of coexisting illness: i.e. heart failure/systemic hypertension, heart failure/pulmonary hypertension, heart failure/diabetes, heart failure/kidney failure, etc. Whether the problem is primarily increased venous back pressure ( preload ), or failure to supply adequate arterial perfusion ( afterload )

  7. Pressure overload - Wikipedia

    en.wikipedia.org/wiki/Pressure_overload

    Pressure overload may affect any of the four chambers of the heart, though the term is most commonly applied to one of the two ventricles. Chronic pressure overload leads to concentric hypertrophy of the cardiac muscle, which can in turn lead to heart failure , myocardial ischaemia or, in extreme cases, outflow obstruction.

  8. Myocardial contractility - Wikipedia

    en.wikipedia.org/wiki/Myocardial_contractility

    An increase in preload results in an increased force of contraction by Starling's law of the heart; this does not require a change in contractility. An increase in afterload will increase contractility (through the Anrep effect). [4] An increase in heart rate will increase contractility (through the Bowditch effect). [4]

  9. Volume overload - Wikipedia

    en.wikipedia.org/wiki/Volume_overload

    Volume overload refers to the state of one of the chambers of the heart in which too large a volume of blood exists within it for it to function efficiently. Ventricular volume overload is approximately equivalent to an excessively high preload. It is a cause of cardiac failure. [1]

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