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A Y-STR is a short tandem repeat (STR) on the Y-chromosome. Y-STRs are often used in forensics , paternity, and genealogical DNA testing . Y-STRs are taken specifically from the male Y chromosome.
The Y-STR markers in the following list are commonly used in forensic [1] and genealogical DNA testing. DYS454 is the least diverse, and multi-copy marker DYS464 is the most diverse Y-STR marker. The location on the Y-chromosome of numbered Y-STR markers can be roughly given with cytogenetic localization. For example, DYS449 is located at Yp11 ...
A person's haplogroup can often be inferred from their STR results, but can be proven only with a Y-chromosome SNP test (Y-SNP test). A single-nucleotide polymorphism (SNP) is a change to a single nucleotide in a DNA sequence. Typical Y-DNA SNP tests test about 20,000 to 35,000 SNPs. [34] Getting a SNP test allows a much higher resolution than ...
STR analysis is a tool in forensic analysis that evaluates specific STR regions found on nuclear DNA. The variable (polymorphic) nature of the STR regions that are analyzed for forensic testing intensifies the discrimination between one DNA profile and another. [3] Scientific tools such as FBI approved STRmix incorporate this research technique.
Y-Chromosome DNA (Y-DNA) testing involves short tandem repeat (STR) and, sometimes, single nucleotide polymorphism (SNP) testing of the Y-Chromosome, which is present only in males and only reveals information on the unbroken paternal line. As with the mitochondria, close matches with individuals indicate a recent common ancestor.
STR analysis can also be restricted to just the Y chromosome. Y-STR analysis can be used in cases that involve paternity or in familial searching as the Y chromosome is identical down the paternal line (except in cases where a mutation occurred). Certain multiplexing kits combine both autosomal and Y-STR loci into one kit further reducing the ...
In the new approach, primers are specially designed to bind closer to the STR region. [32] In normal STR testing, the primers bind to longer sequences that contain the STR region within the segment. MiniSTR analysis, however, targets only the STR location, which results in a DNA product that is much smaller. [32]
In human genetics, a human Y-chromosome DNA haplogroup is a haplogroup defined by specific mutations in the non-recombining portions of DNA on the male-specific Y chromosome (Y-DNA). Individuals within a haplogroup share similar numbers of short tandem repeats (STRs) and single-nucleotide polymorphisms (SNPs). [ 2 ]