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A Basophil granulocyte stains dark purple upon H&E staining. Basophilic is a technical term used by pathologists. It describes the appearance of cells, tissues and cellular structures as seen through the microscope after a histological section has been stained with a basic dye. The most common such dye is haematoxylin.
Basophils are the least common type of granulocyte, representing about 0.5% to 1% of circulating white blood cells. [1] They are the largest type of granulocyte. They are responsible for inflammatory reactions during immune response, as well as in the formation of acute and chronic allergic diseases, including anaphylaxis , asthma , atopic ...
There are four types of granulocytes (full name polymorphonuclear granulocytes): [3] Basophils; Eosinophils; Neutrophils; Mast cells; Except for the mast cells, their names are derived from their staining characteristics; for example, the most abundant granulocyte is the neutrophil granulocyte, which has neutrally staining cytoplasmic granules.
Promyelocytes measure 12–20 microns in diameter. The nucleus of a promyelocyte is approximately the same size as a myeloblast but their cytoplasm is much more abundant. [1] They also have less prominent nucleoli than myeloblasts and their chromatin is more coarse and clumped. [1] The cytoplasm is basophilic and contains primary red/purple ...
In hematology, myelopoiesis in the broadest sense of the term is the production of bone marrow and of all cells that arise from it, namely, all blood cells. [1] In a narrower sense, myelopoiesis also refers specifically to the regulated formation of myeloid leukocytes (), including eosinophilic granulocytes, basophilic granulocytes, neutrophilic granulocytes, and monocytes.
The development of granules continues with the next stage, a myelocyte. At this point, the nucleus is starting to shrink. At this point, the nucleus is starting to shrink. At the stage of a metamyelocyte the cell nucleus is becoming kidney-shaped and it becomes even more bent in the stage of a band cell .
An anterior pituitary basophil is a type of cell in the anterior pituitary which manufactures hormones. It is called a basophil because it is basophilic (readily takes up bases), and typically stains a relatively deep blue or purple. [1] These basophils are further classified by the hormones they produce.
A white blood cell differential is a medical laboratory test that provides information about the types and amounts of white blood cells in a person's blood. The test, which is usually ordered as part of a complete blood count (CBC), measures the amounts of the five normal white blood cell types – neutrophils, lymphocytes, monocytes, eosinophils and basophils – as well as abnormal cell ...