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Other serious side effects include low blood potassium. [7] NPH insulin rather than insulin glargine is generally preferred in pregnancy. [8] After injection, microcrystals slowly release insulin for about 24 hours. [7] This insulin causes body tissues to absorb glucose from the blood and decreases glucose production by the liver. [7]
Some side effects are hypoglycemia (low blood sugar), hypokalemia (low blood potassium), and allergic reactions. [6] Allergy to insulin affected about 2% of people, of which most reactions are not due to the insulin itself but to preservatives added to insulin such as zinc, protamine, and meta-cresol.
The common side effect is low blood sugar. [5] Other side effects may include pain or skin changes at the sites of injection, low blood potassium, and allergic reactions. [5] Use during pregnancy is relatively safe for the baby. [5] Regular insulin can be made from the pancreas of pigs or cows. [2]
Drugs used in diabetes treat types of diabetes mellitus by decreasing glucose levels in the blood.With the exception of insulin, most GLP-1 receptor agonists (liraglutide, exenatide, and others), and pramlintide, all diabetes medications are administered orally and are thus called oral hypoglycemic agents or oral antihyperglycemic agents.
Onset of effects is typically in 90 minutes and they last for 24 hours. [3] Versions are available that come premixed with a short-acting insulin, such as regular insulin. [2] The common side effect is low blood sugar. [3] Other side effects may include pain or skin changes at the sites of injection, low blood potassium, and allergic reactions. [3]
A meta-analysis completed in 2007 and updated in 2020 of numerous randomized controlled trials by the international Cochrane Collaboration found that the effects on blood glucose and glycated haemoglobin A1c were comparable, treatment with glargine and detemir resulted in fewer cases of hypoglycemia when compared to NPH insulin. [24] Treatment ...
Adverse effects include nasopharyngitis, headache, nausea, heart failure, hypersensitivity and skin reactions. [ citation needed ] The U.S. Food and Drug Administration (FDA) is warning that the type 2 diabetes medicines like sitagliptin , saxagliptin , linagliptin , and alogliptin may cause joint pain that can be severe and disabling.
Insulin glargine/lixisenatide, sold under the brand name Soliqua among others, is a fixed-dose combination medication that combines insulin glargine and lixisenatide and is used to treat diabetes. The most common side effects include hypoglycemia (low blood glucose), diarrhea, vomiting and nausea (feeling sick).