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PMA is a diagnosis of exclusion, there is no specific test which can conclusively establish whether a patient has the condition.Instead, a number of other possibilities have to be ruled out, such as multifocal motor neuropathy or spinal muscular atrophy.
Motor neuron diseases affect both children and adults. [5] While each motor neuron disease affects patients differently, they all cause movement-related symptoms, mainly muscle weakness . [ 6 ] Most of these diseases seem to occur randomly without known causes, but some forms are inherited. [ 2 ]
Pulmonary Arterial Hypertension (PAH) is a syndrome in which the blood pressure in the pulmonary arteries and pulmonary arterioles (the blood vessels located proximal to the capillary bed, the site of oxygen exchange in the lungs) is elevated.
A ratio of 1.0 is suggested as a cutoff in adults. [62] Cutoff ~1.09 in children. [62] Increased diameter ratio of segmental arteries to bronchi. This finding in three or four lobes, in the presence of a dilated pulmonary trunk (≥29 mm), and absence of significant structural lung disease confers a specificity of 100% for pulmonary ...
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Selexipag, sold under the brand name Uptravi, is a medication developed by Actelion for the treatment of pulmonary arterial hypertension (PAH). [ 3 ] [ 4 ] Selexipag and its active metabolite , ACT-333679 (or MRE-269, the free carboxylic acid ), are agonists of the prostacyclin receptor , which leads to vasodilation in the pulmonary circulation ...
Consumers post reviews, photos, and questions in a discussion format, and also post questions to providers. RealSelf also hosts a directory of doctors organized by specialty, the treatment offered, and location. Consumers can contact doctors through the site, who sometimes have special offers available. RealSelf also has an iOS app.
Eisenmenger syndrome or Eisenmenger's syndrome is defined as the process in which a long-standing left-to-right cardiac shunt caused by a congenital heart defect (typically by a ventricular septal defect, atrial septal defect, or less commonly, patent ductus arteriosus) causes pulmonary hypertension [1] [2] and eventual reversal of the shunt into a cyanotic right-to-left shunt.