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Some antidepressants, including commonly prescribed ones from the class known as SSRIs (selective serotonin reuptake inhibitors), can cause sexual side effects such as erectile dysfunction ...
Experiments with pharmacological agents that cause depletion of monoamines have shown that this depletion does not cause depression in healthy people. [ 61 ] [ 62 ] Another problem that presents is that drugs that deplete monoamines may actually have antidepressants properties.
Late-life depression is often underdiagnosed, which is due to numerous reasons, including that depressed mood is commonly not as prominent as other somatic and psychotic symptoms such as loss of appetite, disruptions in sleep, lack of energy or anergia, fatigue, and loss of interest and enjoyment in normal life activities.
Chemically, it is a secondary amine dibenzocycloheptene and pharmacologically it is classed as a first-generation antidepressant. [36] Nortriptyline may also have a sleep-improving effect due to antagonism of the H 1 and 5-HT 2A receptors. [37] In the short term, however, nortriptyline may disturb sleep due to its activating effect.
Sleep disorders and depressive disorders are linked to obesity and magnesium deficiency, so magnesium supplements may pack a one-two punch for weight loss. More research is needed on this, though.
Certain antidepressants may cause emotional blunting, characterized by reduced intensity of both positive and negative emotions as well as symptoms of apathy, indifference, and amotivation. [ 82 ] [ 83 ] It may be experienced as either beneficial or detrimental depending on the situation. [ 84 ]
As Americans are increasingly reaching for pharmaceutical solutions for depression—about one in eight U.S. adults takes antidepressants—scientists have been innovating novel treatments for it.
This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...
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