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Its use during pregnancy is contraindicated, although it has been placed in Australian pregnancy category C. [13] Its use during the first trimester (during organogenesis) and 12 weeks prior to pregnancy has been associated with an increased risk of congenital malformations, especially malformations associated with maternal folic acid ...
Gestational diabetes is a form of diabetes that is first diagnosed during pregnancy and can accordingly cause high blood sugar that affects the woman and the baby. [9] In 10 - 20% of women whose diet and exercise are not adequate enough to control blood sugar, insulin injections may be required to lower blood sugar levels. [9]
Based on the studies that show that trimethoprim crosses the placenta and can affect folate metabolism, there has been growing evidence of the risk of structural birth defects associated with trimethoprim, especially during the first trimester of pregnancy. [21] The trophoblasts in the early fetus are sensitive to changes in the folate cycle.
The heart adapts to the increased cardiac demand that occurs during pregnancy in many ways. Cardiac output (Lit./Min.): 6.26; Stroke Volume (Ml.): 75; Heart Rate (Per min.): 85; Blood Pressure: Unaffected; Cardiac output increases throughout early pregnancy, and peaks in the third trimester, usually to 30-50% above baseline. [6]
Hypertensive disorders during pregnancy, such as gestational hypertension, preeclampsia, and eclampsia, are a major contributor to maternal and fetal illness and death on a worldwide scale. Around 5-10% of pregnancies are affected by these conditions, with preeclampsia being responsible for up to 14% of maternal deaths globally.
Severe and disseminated coccidioidomycosis has been reported to occur in increased frequency in pregnant women in several reports and case series, but subsequent large surveys, with the overall risk being rather low. [1] Varicella occurs at an increased rate during pregnancy, but mortality is not higher than that among men and non-pregnant ...
Exercise during pregnancy can help prevent hypertension as it can improve not only health for the mother but also the child. Exercise can regulate the energy needs required during pregnancy while also decreasing inflammation. Regular exercise can also lower the increased stress levels associated with pregnancy. [8]
Proarrhythmia is a new or more frequent occurrence of pre-existing arrhythmias, paradoxically precipitated by antiarrhythmic therapy, which means it is a side effect associated with the administration of some existing antiarrhythmic drugs, as well as drugs for other indications.
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