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Pantoprazole is a proton-pump inhibitor (PPI) and its effectiveness is similar to that of other PPIs. [8] It is available by mouth and by injection into a vein. [5] Common side effects include headaches, diarrhea, abdominal pain, and joint pain.
PPIs may induce common side effects including headache, diarrhoea, abdominal pain, and nausea. Taking PPI may rarely cause community-acquired pneumonia . Prolonged use of PPI may be associated with intestinal Clostridioides difficile infection , low magnesium level , Vitamin B12 and iron deficiency, osteoporosis , acute kidney inflammation, and ...
In general, proton pump inhibitors are well tolerated, and the incidence of short-term adverse effects is relatively low. The range and occurrence of adverse effects are similar for all of the PPIs, though they have been reported more frequently with omeprazole. This may be due to its longer availability and, hence, clinical experience.
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A known side effect of bismuth salts is harmless and reversible darkening of tongue and stool by formation of bismuth sulfite. [3] Other side effects of bismuth containing combination therapies are often difficult to assign to a specific component. [citation needed]
Truncal vagotomy is a treatment option for chronic duodenal ulcers. [5] [6] It was once considered the gold standard, but is now usually reserved for patients who have failed the first-line "triple therapy" against Helicobacter pylori infection: two antibiotics (clarithromycin and amoxicillin or metronidazole) and a proton pump inhibitor (e.g., omeprazole).
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Serious side effects may include angioedema, Clostridioides difficile infection, and pneumonia. [11] Use in pregnancy appears to be safe, while safety during breastfeeding is unclear. [ 3 ] Esomeprazole is the ( S )-(−)- enantiomer (or less specifically the S- isomer ) of omeprazole . [ 11 ]
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