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Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives . [ 5 ] It is also available in drug combinations such as loratadine/pseudoephedrine , in which it is combined with pseudoephedrine , a nasal decongestant . [ 5 ]
For instance, if the ADI is based on data from humans the safety factor is usually 10 instead of 100. The ADI is usually given in mg per kg body weight. [5] The ADI is considered a safe intake level for a healthy adult of normal weight who consumes an average daily amount of the substance in question.
A Clarinase Repetab tablet contains 5 mg loratadine in the tablet coating and 120 mg pseudoephedrine sulfate equally distributed between the tablet coating and the barrier-coated core. The two active components in the coating are quickly liberated; release of pseudoephedrine in the core is delayed for several hours.
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In single-dose scenarios, the patient's body weight and the drug's recommended dose per kilogram are used to determine a safe one-time dose. If multiple doses of treatment are needed in a day, the physician must take into account information regarding the total amount of the drug which is safe to use in one day, and how that should be broken up ...
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