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Leptospirosis is a blood infection caused by the bacterium Leptospira [8] that can infect humans, dogs, rodents and many other wild and domesticated animals. [8] Signs and symptoms can range from none to mild ( headaches , muscle pains , and fevers ) to severe ( bleeding in the lungs or meningitis ). [ 5 ]
Leptospira noguchii is another pathogenic bacteria that causes Leptospirosis. Leptospirosis can be transferred in a multitude of ways. Leptospirosis can transfer from animals to humans , humans to humans, or animals to animals via intake of contaminated body fluids, such as urine and blood. [7]
Leptospires also has LipL32 surface protein that binds to fibroblast, macrophages, endothelial cells, and kidney epithelial cells. Examples of complement regulators are: Factor H, C4b binding protein, and vitronectin. Examples of cytokines are: IL-6, TNF, and IL-10.
Leptospira (from Ancient Greek λεπτός (leptós) 'fine, thin, narrow, etc.' and Latin spira 'coil') [1] is a genus of spirochaete bacteria, including a small number of pathogenic and saprophytic species. [2]
Leptospirosis: Caused by bacterium of genus Leptospira: Water contaminated by the animal urine carrying the bacteria Begins with flu-like symptoms then resolves. The second phase then occurs involving meningitis, liver damage (causes jaundice), and kidney failure: Otitis Externa (swimmer's ear) Caused by a number of bacterial and fungal species.
Conjunctival suffusion is an eye finding occurring early in leptospirosis, which is caused by Leptospira interrogans.Conjunctival suffusion is characterized by redness of the conjunctiva that resembles conjunctivitis, but it does not involve inflammatory exudates. [1]
The Leptospiral culture collection consists of over 300 different types of Leptospira cultures and is one of only several collections of its kind in the world. [1] The work of the laboratory supports the fight against the disease by providing analysis and diagnostic support to public and private pathology providers, both nationally and internationally.