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A corepressor downregulates (or represses) the expression of genes by binding to and activating a repressor transcription factor. The repressor in turn binds to a gene's operator sequence (segment of DNA to which a transcription factor binds to regulate gene expression), thereby blocking transcription of that gene.
Transcription factor glossary; gene expression – the process by which information from a gene is used in the synthesis of a functional gene product such as a protein ...
The California Code of Civil Procedure (abbreviated to Code Civ. Proc. in the California Style Manual [a] or just CCP in treatises and other less formal contexts) is a California code enacted by the California State Legislature in March 1872 as the general codification of the law of civil procedure in the U.S. state of California, along with the three other original Codes.
The nuclear receptor co-repressor 1 also known as thyroid-hormone- and retinoic-acid-receptor-associated co-repressor 1 (TRAC-1) is a protein that in humans is encoded by the NCOR1 gene. [ 5 ] [ 6 ] NCOR1 is a transcriptional coregulatory protein which contains several nuclear receptor interacting domains.
Alignment of the two proteins indicated that they had a largely common domain structure, suggesting parallels in their mode of action. Mitch Lazar's group has shown that inactive nuclear receptors recruit corepressors in part through amphipathic helical peptides called CoRNR boxes, which are similar to the coactivator nuclear receptor boxes.
Another quirk is that because the superior courts are now fully unified with all courts of inferior jurisdiction, the superior courts must hear relatively minor cases that previously would have been heard in such inferior courts, such as infractions, misdemeanors, "limited civil" actions (actions where the amount in controversy is below $35,000), and "small claims" actions.
Group 3 (KLFs 9,10,11,13,12, and 16) have repressor activity via interaction with the common transcriptional co-repressor, Sin3A. KLFs 15 and 17 are distantly related without any defined protein interaction motifs. [4] The Sp family members diverged from KLFs since Filozoa. They are typically divided into two groups of Sp1-4 and Sp5-9.
A common name, in the nomenclature of biology, is a name of a taxon or organism based on the normal language of everyday life. Common name may also refer to: Common name (chemistry) (also: trivial name), non-systematic name for a chemical; Common noun in linguistics, noun that refers to a class of entities rather than a unique entity